Apoptotic Cells Secrete Angiogenic Factors
It is a medical mystery why approaches such as extracorporeal ozone therapy or even photopheresis seem to have therapeutic effects in certain situations. One possibility is that stressing of cells outside of the body causes formation of apoptotic bodies, with the apoptotic bodies having a therapeutic effect.
The possibility of apoptotic bodies... [Read more]
Hair Stem Cells for Injured Nerves
Sagamihara, Japan -
Hair follicle stem cells have previously been demonstrated to possess various characteristics of other stem cells, including migration to SDF-1, thus potentially allowing intravenous injection. Also this stem cell population has been proposed, along with adipose stem cells, to have immune... [Read more]
Pulmonary Fibrosis Treated by Mesenchymal Stem Cells
Melbourne, Australia -
Systemic administration of stem cells is usually associated with preferential localization into the lung and liver. Lung conditions such as acute respiratory distress syndrome have no cure with exception of transplantation, which is limited to a small number of patients. The rationale of using mesenchymal stem cells for pulmonary diseases comes from... [Read more]
Free bone allograft prevents acute immune reaction
London, Canada -
Antibody-mediated acute vascular rejection (AVR) is a major problem in organ transplantation. The C3H to BALB/c heterotopic (second heart) cardiac transplant model resembles the human condition of AVR. When recipients are given a course of the conventionally used immune suppressant agent cyclosporin A, grafts survive 15 days. This is approximately 8 days... [Read more]
G-CSF Makes You Smarter
Münster, Germany -
G-CSF is widely used as a stem cell mobilizer, inducing complement-dependent exit of CD34 and mesenchymal stem cells from the bone marrow. It has been postulated that G-CSF has not just hematopoietic but also neurogenic activity. For example, a study reported that G-CSF administration... [Read more]
Mouse Liver Failure Treated by Human Cord Blood Stem Cells
Sacramento, CA -
It is known that administration of autologous bone marrow cells into patients with liver failure induces clinical improvement, at least in pilot trials of cirrhotic patients. Mechanistically this may work through the process of transdifferentiation, that is, bone marrow directly differentiating to... [Read more]
- Neuroprotective Stem Cell Secreted Peptides
- Allogeneic rejection of embryonic stem cells
- Medistem Fat Stem Cells Help Multiple Sclerosis Patients
- Low Oxygen Tension for Cancer Stem Cells: Keeping it Real
-
Stem cells improve post-infarct heart function
|
1 Comment
Stromal antigen-presenting cells and use thereof
Mesenchymal stem cells are known to possess a variety of immune modulatory activities such as suppression of allogeneic responses, as well as induction of T regulatory cells. Mechanisms include expression of IDO and
- Patent Spotlight - Stromal antigen-presenting cells and use thereof - 7,553,661
- Dedifferentiated, programmable stem cells of monocytic origin, and their production and use - 7,553,663
- Directed in vitro differentiation of marrow stromal cells into neural cell progenitors - 7,547,545
- Progenitor cells from wharton's jelly of human umbilical cord - 7,547,546
- Methods for identifying factors for differentiating definitive endoderm - 7,541,185
- Method of generating human retinal progenitors from embryonic stem cells - 7,541,186
- Method of expanding undifferentiated hemopoietic stem cells - 7,534,609
- Pregnancy-induced oligodendrocyte precursor cell proliferation regulated by prolactin - 7,534,765
- Growth and differentiation of adult muscle stem cells with activators or inhibitors of Wnt signaling - 7,541,183
- Angiogenically effective unit dose of FGF-2 and method of use - 7,541,333
- Stem cells and their use in transplantation - 7,537,756
- Methods of producing pancreatic hormones - 7,534,608