Category: Cardiac (26)
Interferon gamma as a "danger signal"
Boston, MA -
Although stem cell therapy has demonstrated some benefit in a variety of cardiac conditions, heart transplantation is still the only option for many patients with end-stage heart failure. The problem with heart transplantation is that firstly there are not enough donors, and secondly, the patients have to take immune suppressive...
Stem Cell Cytokines Preventing Ischemia Reperfusion
Osaka, Japan -
Granulocyte colony stimulating factor (G-CSF) is one of the largest selling products of the biotechnology industry. Approved uses of this recombinant cytokine include stimulation of neutrophil production after chemotherapy or bone marrow transplantation. Another use is in mobilizing the hematopoietic stem cells to... Indianapolis, Indiana -
It is safe to say that the actual implimentation of stem cell therapy clinically is actually more being performed for purposes of immune modulation than actually growing of new tissues. For example, mesenchymal stem cells are most advanced clinically in the USA by the company Osiris, which are... Warsaw, Poland -
The immune system is activated in response to Danger signals, which evoke various innate molecular pathways that culminate with inflammatory cytokine production and eventual activation of the adaptive immune system. Stem cells circulating in lymphatics have been implicated in recognizing classical danger signals... Yamaguchi, Japan -
The ability of various mesenchymal stem cell populations and CD34 stem cell populations to help in stimulation of cardiac regeneration is a current belief by many investigators. Although some positive in vivo data have been... Chicago, IL -
The use of stem cells for myocardial repair was originally proposed after mouse studies demonstrated what appeared to be human bone marrow derived stem cells differentiating into myocardium. Subsequently, these experiments were translated into clinical studies, which utilized autologous bone marrow cells as sources... Valencia, Spain -
Mesenchymal stem cells have been detected in bone marrow, peripheral blood, muscle and even in menstrual blood.
Another... Los Angeles, CA -
It is known that mesenchymal stem cells are useful for treating patients after a heart attack. What is however unknown is exactly how these cells mediate their effects. On the one hand mesenchymal stem cells are known to inhibit various inflammatory... Cincinnati, OH -
Commercialization of stem cell therapy is difficult since sometimes one doesn't really know what the product is. Additionally, there could be many products that are developed that are used in the implimentation of a single therapy.
A current publication (Pasha et al. Preconditioning Enhances Cell Survival and Differentiation of Stem Cells during Transplantation in... The University of Latvia hosted an international conference entitled “Stem Cells and Cell Therapy” on November 2nd, 2007. StemCellPatents.com sent a representative to observe the meeting.
Meeting organizer Dr Janis Ancans provided an overview of the state of the art in stem cell research, followed by data describing characterization of dermal, adipose, and bone marrow derived stem cell...
IL-18 in the Heart
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Importance of the Injury Signal
1 Comment
TGF-beta stimulating bone marrow to cardiac in vitro
Autologous G-CSF mobilized CD34 for angina
Tooth stem cells for heart attack
Hepatocyte Growth Factor Helps After Heart Attack
Giving stem cells a kick in vitro with stromal derived factor-1
Latvian Stem Cell Meeting Success