Category: Cardiac (25)
Adipose Stem Cells With Telomerase and Myocardin A
Houston, Texas - One of the main concerns regarding adult stem cells that is often mentioned is their limited expression of telomerase in contrast to embryonic stem cells. In a recent study (Madonna et al. Myocardin A Enhances Telomerase Activities in Adipose Tissue Mesenchymal Cells and Embryonic Stem Cells Undergoing Cardiovascular Myogenic Differentiation. em Cells. 2007 Oct 4) it was...
Heart Failure Recovery After Adult Stem Cell Therapy
[Watch the Video] This is a video of a heart failure patient describing a remarkable recovery after treatment with adult stem cells.
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Stem Cells Mobilized by Heart Attacks
[Watch the Video] This video discusses how heart attacks generate VEGF which mobilizes stem cells to leave the bone marrow and enter systemic circulation, presumably on the way to the heart. Interestingly, the paper reviewed in the video was published in 2001. Since then numerous other studies have demonstrated VEGF and other...
From Sperm to Heart...well kind of...
Göttingen, Germany -
Pluripotent stem cells derived from primordial germ cells have been previously described. What is more exciting is the possibility of using adult testicular cells as a source of pluripotent stem cells. This was actually published in Nature last year (Guan et al. Pluripotency of spermatogonial... Taipei, Taiwan -
Valproic acid is a clinically used anti-convulsant administered for bipolar disorder and epilepsy. It also expands stem cells in vitro. In a recent paper (Lee et al. Inhibition of Histone Deacetylase on Ventricular Remodeling in Infarcted Rats. Am J Physiol Heart Circ Physiol. 2007 Mar 30) it was demonstrated... Atlanta, USA -
Muscle satellite cells are located beneath the myofiber basal laminae (under the basement membrane surrounding each myofiber) and close to capillaries. They play a critical role in repair and turn over of muscle, acting as a supply of progenitor cells.
In a recent paper (Bondesen et al. Inhibition of myoblast migration by prostacyclin is... Rostock, Germany -
Anti-inflammatory and regenerative abilities of mesenchymal stem cells are well-known. In fact, the first non-hematopoietic clinically approved use of stem cells is most likely to occur with Osiris's mesenchymal stem cell products which are in Phase III of clinical trials.
The important question scientists have to ask themselves is what is the...
Valproic Acid for Cardiac Remodeling
Double Blind Study of Stem Cells for Heart Failure
Treating Heart Failure With Bone Marrow Stem Cells
PGI2 Regulates Myogenesis
bcl-2 tx: Long Live Mesenchymal Stem Cells
Young stem cells for cardiac health