Category: Use (72)
Allogeneic MSC for Restenosis
Naples, Italy -
The inherent antiinflammatory activities of mesenchymal stem cells have been leveraged for treatment of diseases associated with uncontrolled production of inflammatory mediators such as graft versus host disease and Crohn's Disease. Indications for which mesenchymal stem cells are currently in
Go Cytori Go !
Tokyo, Japan -
One of the issues of adult stem cell therapy is processing. When using allogeneic cells, for example, Endometrial Regenerative Cells, the cells can be made at a dedicated facility and shipped to where needed. On the other hand, autologous cells present a little more difficulty since: a) people don't like having holes drilled in their...
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HGF-1 Double Blind Trial for Critical Limb Ischemia
Durham, NC -
Stimulation of angiogenesis has previously been demonstrated using various cell therapy methods, such as administration of autologous bone marrow stem cells either in the heart or ischemic leg muscle. Autologous approaches sometimes are difficult since on the one hand they require cellular processing, which...
Mesenchymal Stem Cells Augmented by Estrogen
Indianapolis, Indiana -
Mesenchymal stem cells, have very potent therapeutic potential because they can be used in an allogeneic manner, they can differentiate into many new types of tissue, and they produce numerous growth factors. Mesenchymal stem cells have been demonstrated in non-clinical systems to be effect in
Duchenne Muscular Dystrophy Calls Stem Cells
Milan, Italy -
Duchenne Muscular Dystrophy is a lethal genetic condition, characterized by progressive muscle weakness caused by mutations in the dystrophin gene. Approaches to treatment of this condition have included the use of cord blood stem cells, however little functional improvement is seen, even in animal models. US patent 2 Comments
Mesenchymal stem cells made into nucleus pulposus cells
Lumbar disc degeneration is a significant cause of morbidity. Given that the key cells maintaining the mass of the disc are nucleus pulposus cells, one of the aims in regenerative medicine has been to treat disc degeneration by administration of stem cells.
However, one major question arises, would it be more beneficial to administer stem...
Treating back pain with mesenchymal stem cells
Pittsburgh, Pennsylvania -
Vertebral disc degeneration is a major cause of suffering internationally. Although various interventions exist, such as disc replacement and surgical fusion, these have numerous long-term limitations such as need for resurgery, degeneration of the adjacent disc, and relapse of pain. One exciting method of treating...
Mesenchymals for wound healing
Nara Medical University, Japan - Mesenchymal stem cells are classically defined as CD34 negative, CD45 negative, SH2 and SH4 positive, and Thy-1 (CD90) positive cells. Therapeutically mesenchymal stem cells are attractive because they do not require matching with recipients, supposedly...
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Breast cancer FGF-2 and VEGF calls in mesenchymal stem cells
Augusta, Georgia - It is believed by many that tissue resident stem cells subsequent to accumulating DNA damage lose proliferative controls and transform into tumors. For example, there is a classical study in which mice were infected with h.pylori and gastric cancer was allowed to develop. Strikingly, the gastric cancer was derived from bone marrow stem cells...
Velcade guides stem cells to bone
Boston, Massachusetts - Stem cell therapeutics are difficult to commercialize because of the need for cellular manipulation. Even business models that involve off the shelf universal stem cells have the issue that you need are selling an actual biologic product, a product that is very difficult to standardize and ensure quality...
2 Comments