Category: Use (71)
Stem Cell Therapy for Urinary Stress Incontinence
Innsbruck, Austria -
Stress incontinence means having to urinate as a result of coughing, sneezing, laughing, or exercise. Usually this condition is associated with muscular dysfunction or damage.
In a recent paper (Strasser et al. Autologous myoblasts and fibroblasts versus collagen for treatment of stress urinary incontinence in women: a randomised controlled trial. Lancet. 2007... Verona, Italy -
Mesenchymal stem cells are currently in Phase III of clinical trials in the US and are available as a fee for service in places such as Cellmedicine for the treatment of autoimmune/inflammatory conditions.
A fundamental question, however, is what are the mechanisms by which mesenchymal stem cells inhibit... Sichuan, China -
We have previously discussed that HLA-G expression is an important mechanism by which mesenchymal stem cells suppress the immune system. In a recent paper (Yie et al. Expression of human leucocyte antigen G (HLA-G) is associated with prognosis in non-small cell lung cancer. Lung Cancer... Cedex, France -
The fact that mesenchymal stem cells are immune suppressive is established. This is one of the reasons why companies such as Osiris are trying to get them approved as an "off the shelf" product that does not require matching.
Several mechanisms are known by which mesenchymal stem cells suppress the immune responseSunday August 5th, 2007 @ 18:38:12 EST
Mesenchymal Stem Cells and IDO
HLA-G Helps Lung Cancer Escape Immune System
Mesenchymal Stem Cells Use HLA-G to Suppress T Cells
MS Patient After Stem Cell Therapy
[Watch the Video] Numerous animal studies support the immunomodulatory activities of stem cells, especially mesenchymal stem cells. For example, expression of molecules such as IDO, IL-10 and TGF-beta by mesenchymal stem cells allows induction of tolerance, generation of Treg cells, as well as veto-like activity. Although there are...
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Insulin transfected mesenchymals for diabetes
Nantong, China - While numerous groups are trying to treat diabetes by inducing differentiation of stem cells into insulin producing cells, other groups are simply transfecting the gene for insulin (or proinsulin) into stem cells and administering the cells. While transfection ensures that the gene will be expressed, it does not...
DNA Immunization for Cancer
[Watch the Video] This video describes a publication that uses "naked" DNA to immunize patients with prostate cancer so as to induce immunity to the antigen PSA. While, T cell mediated immunity was induced, this was primarily in patients treated with higher vaccine doses. The relevance of this to the stem cell community is that as we start identifying...
Stem Cell Therapy for Cerebral Palsy
[Watch the Video] This video describes the scientific rationale for utilization of stem cells to treat cerebral palsy. Few people know that cerebral palsy was treated by Dr. Kurtzburg from Duke using cord blood stem cells. This is described in the video.
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G-CSF for Spinal Cord Injury
Newark, NJ - Numerous stem cell therapeutic approaches are currently under investigation for spinal cord injury. Although it has been demonstrated in animal models that stem cells possess various repairative properties, an important and often overlooked property of stem cells is their ability to produce numerous trophic factors capable of stimulating endogenous healing processes. In a...
Stem Cell Treatment for Autism
Stem Cell Clinic Publishes First Peer Reviewed Paper on Autism Stem Cell Therapy SAN DIEGO--(BUSINESS WIRE)--The Institute for Cellular Medicine (www.cellmedicine.com) announced today what appears to be the first publication in a peer reviewed journal outlining scientific rationale for the use of stem cells in the treatment of...
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