Category: Hepatic (13)

Mesenchymal stem cells to liver

Hangzhou, China - The ability of bone marrow derived mesenchymal cells to differentiate into various lineages is well-known. A recent paper (Chen et al. Hepatocytes induced by conditioned culture medium of hepatocytes. J Cell Biochem. 2007 Mar 5;) describes a novel protocol for inducing differentiation of mesenchymal stem cells into hepatocytes. Essentially, mesenchymal stem cells were...

Liver regeneration by inhibiting the inhibitor

Kayseri, Turkey - Readers of StemCellPatents.com will be familiar with patents describing the inhibition of TGF-beta as a means of stimulating stem cell proliferation. Essentially, it is known in the hematopoietic system at least, that autocrine production of TGF-beta by stem...

ES cells to Hepatocytes

Bethesda MD - Readers of StemCellPatents.com are familiar with the patent of Loren Field which teaches that tissue-specific promoters can drive expression of markers from embryonic stem cell cultures so as to be able to selectively "fish out" stem cells that are starting to commit to a specific lineage. In a recent paper (Heo...