News Posts
Making stem cells find apoptotic cells
Torino, Italy -Hematopoietic stem cells and mesenchymal stem cells are known to more or less find their way to injured tissue. This is one of the reasons why companies such as Osiris can get away with simply intravenously injecting their mesenchymal stem cells and still get potent...Wednesday October 8th, 2008 @ 21:06:39 EST
ES cells as immune modulators: look out MSCs !!
Ein Kerem, Israel -As you may have noticed, we at StemCellPatents.com seem to stay way from the whole politics of this "embryonic stem cell debate". The main reason being that there have been numerous advances made in the area of adult stem cells, already being in Phase III of clinical trials, while formal US clinical trials of embryonic stem cells have not even been...Sunday October 5th, 2008 @ 21:20:25 EST
Cancer Vaccine Against Aurora Kinase
Ehime, Japan -Cancer vaccines are attractive because of their general lack of toxicity, their ability to selectively destroy malignant tissue, as well as possibility of preventing micrometastasis. Immunotherapy of cancer has been attempted for more than a century, however conflicting results and lack of clear-cut benefit in Phase III trials has...Thursday October 2nd, 2008 @ 10:51:49 EST
Selecting for better mesenchymal stem cells
New Orleans, LA - Mesenchymal stem cells have made significant therapeutic advances with positive clinical results in heart disease, Crohn's, and GVHD. The question is, "how to improve efficacy?"Mesenchymal stem cell powerhouse Dr. Darwin Prockup published a recent paper (Lee et al. The CD34-like protein PODXL and...Saturday September 27th, 2008 @ 21:46:45 EST
Exercise Increases Neural Stem Cells
Taiwan - Neural stem cells are known to exist in post-natal animals. For example, during pregnancy, an increase in mitotic cells has been reported in the brains of the mother. This has been ascribed to numerous hormones and growth factors, including prolactin and human chorionic gonadotrophin. Furuta et al. (Gestation-induced cell proliferation in the rat brain. Brain Res Dev Brain Res...Monday September 22nd, 2008 @ 09:58:03 EST
Low Hematopoietic Stem Cells in Alzheimer's?
Tübingen, Germany -The chemokine SDF-1 is known to attract hematopoietic stem cells and mesenchymal stem cells. Under basal conditions it is produced by the bone marrow stromal cells, this is why hematopoietic stem cell transplants can be performed by intravenous administration and they find their way back to the bone...Friday September 12th, 2008 @ 23:29:24 EST
Chronic Inflammation Inhibits Endogenous Neural Stem Cells
Valencia, Spain -Mesenchymal stem cells are widely known to possess anti-inflammatory and immune modulatory activity. The regenerative and trophic functions of this type of stem cell may actually be less important than their ability to block pathological cytokine expression. In fact, the first non-hematopoietic stem cell...Tuesday September 2nd, 2008 @ 15:17:43 EST
Why the hype about in vivo reprogramming?
Cambridge, MA-You may have seen the widespread media coverage last week describing the "reprogramming" of pancreatic cells into insulin producing "islet-like cells". Essentially, all the buzz was about a paper (Zhou et al. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 2008 Aug 27) in which differentiated pancreatic exocrine cells (not the...Sunday August 31st, 2008 @ 17:08:24 EST
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Limbs Saved by Medistem's Endometrial Regenerative Cells
San Diego CA-A publication (Murphy et al Allogeneic endometrial regenerative cells: An "off the shelf solution" for critical limb ischemia? J Transl Med. 2008 Aug 19;6(1):45) led by the internationally renowned vascular surgeon Dr Michael Murphy...Sunday August 24th, 2008 @ 17:29:22 EST