News Posts
Valencia, Spain -
Mesenchymal stem cells have been detected in
bone marrow,
peripheral blood,
muscle and even in
menstrual blood.
Another...
Monday December 17th, 2007 @ 04:20:06 EST
Taipei, Taiwan -
In addition to their known ability to differentiate into
muscle,
bone, and
neuronal cells, mesenchymal stem cells have been demonstrated to have the ability to differentiate into
Monday December 17th, 2007 @ 03:38:27 EST
2 Comments
Shanghai, China -
Mesenchymal stem cells are very useful since they can be administered across allogeneic barriers without need for immune suppression and can be differentiated into various tissues such as
liver.
In a current paper (Dai et al. Stimulation of osteogenic activity in mesenchymal stem cells by FK506. J Biomed Mater...
Monday December 17th, 2007 @ 01:12:56 EST
Los Angeles, CA -
It is known that
mesenchymal stem cells are useful for treating patients after a heart attack. What is however unknown is exactly how these cells mediate their effects. On the one hand mesenchymal stem cells are known to
inhibit various inflammatory reactionsTuesday December 11th, 2007 @ 18:08:51 EST
Toronto, Canada -
Exendin-4 is an agonist of GLP-receptor 1, which is involved in not only increasing the mass of pancreatic beta cells, but has also been implicated in the
stimulation of new neuron generation. In addition to exendin-4, agonists of the glucagon-like receptor include various incretin hormones.
In a recent paper...
Tuesday December 11th, 2007 @ 02:54:12 EST
1 Comment
Chengdu, China -
The use of mesenchymal stem cells is now a "clinical reality"http://www.stemcellpatents.com/news-show-154, primarily for the treatment of diseases such as
multiple sclerosis and other inflammatory conditions. This is due to the known ability of mesenchymal stem cells to differentiate into various tissues, and also to...
Monday December 10th, 2007 @ 03:20:53 EST
Burlington, VT -
Generation of lung epithelium de novo would be very useful in the treatment of chronic lung diseases. Unfortunately previous attempts to do this have not been extremely successful. In a recent study (Sueblinvong et al. Derivation of Lung Epithelium From Human Cord Blood-Derived Mesenchymal Stem Cells. Am J Respir Crit Care Med. 2007 Dec 6) human cord blood stem cells were...
Monday December 10th, 2007 @ 02:59:41 EST
1 Comment
Boston, MA -
A potentially new role for stem cells has been described. In most cases, various stem cells such as
mesenchymal stem cells as well as
hematopoietic stem cells possess immune suppressive characteristics. In a recent publication (Massberg et al...
Wednesday December 5th, 2007 @ 11:20:16 EST
Erlangen, Germany -
Although mesenchymal stem cells are primarily known for their
differentiation abilities, the first clinical trials, and most likely BLA grantings, will be for immune modulation by these cells in the conditions of graft versus host disease and Crohn's disease.
In the same way that
Wednesday December 5th, 2007 @ 04:38:55 EST
Tokyo, Japan -
It is generally known that early, non-proliferative stem cell reserves are sequestered in hypoxic niches.
In a recent paper (Kubota et al. Bone marrow long label-retaining cells reside in the sinusoidal hypoxic niche. Biochem Biophys Res Commun. 2007 Nov 26) histological assessment was performed of cells in hypoxic niches of the bone marrow. The investigators analyzed BrdU...