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Stem Cell Therapy for Multiple Sclerosis

[Watch the Video]The use of stem cells for treatment of multiple sclerosis has the potential to address both the inflammatory aspects of the disease, as well as induce regeneration.  Above is a clip from a news release describing what appears to be a repeatedly successful treatment of multiple sclerosis using the patient's own...
Monday March 2nd, 2009 @ 20:41:36 EST

TNF alpha inhibits SDF-1 increases osteoclast precursors

Rochester, NY -It is known that inflammatory mediators, such as interferon gamma, under chronic conditions are generally suppressive of hematopoiesis, whereas under acute conditions hematopoiesis is actually enhanced by inflammatory mediators.  In a recent paper (Zhang et al. TNF inhibits production of stromal cell-derived factor 1 by bone stromal cells and...
Monday March 2nd, 2009 @ 02:17:27 EST

EPO Protects from Mouse Multiple Sclerosis

 [Watch the Video]New Jersey, USA -There are many studies discuss immune modulation by stem cells by mechanisms such as IDO production, soluble HLA-G, and hepatocyte growth factor.  An interesting question is whether stimulators of various stem cell activities may have immune modulatory activity as...
Thursday February 26th, 2009 @ 12:13:20 EST 1 Comment

Stem Cell Inhibition of Multiple Sclerosis by IDO Induction

[Watch the Video] Lodz, Poland -One of the very interesting things is trying to figure out how stem cells mediate their therapeutic effects in conditions such as multiple sclerosis.  In general there are three main ways: 1) Differentiation into neurons/oligodendrocytes; 2) Secrete growth factors; and 3) Sunday February 22nd, 2009 @ 23:52:52 EST

Resistance to Fas Induced Apoptosis in Glioma Stem Cells

Cedex, France -The cancer stem cell appears to exist as a small fraction of the tumor mass that it relatively quiescent and resistant to killing by numerous types of chemotherapies because it has a set of drug efflux pumps.  One characteristic of cancer stem cells in tissues such as colon, lung, and Friday February 13th, 2009 @ 12:46:47 EST

Mesenchymal Stem Cells Inhibit Gamma Delta T Cell Proliferation

Toulouse, France -We have previously discussed that mesenchymal stem cells inhibit T cell proliferation, activate suppressor T cells, inhibit homeostatic T cell expansion and can be used as universal donors in some situations due to their hypoimmunogenic activies as well as...
Tuesday February 10th, 2009 @ 02:10:42 EST

Endometrial Regenerative Cells Inhibit Glioma

San Diego, CA -Endometrial Regenerative Cells (ERC) are a population of adherent pluripotent stem cells that share certain features with mesenchymal stem cells such as ability to differentiate into bone, cartilage and fat, as well as numerous surface markers (CD90, CD105, CD73).  Interestingly, endometrial regenerative cells also have some...
Sunday February 8th, 2009 @ 18:57:09 EST 1 Comment

Periodontal Ligament Mesenchymals are Immune Suppressive

Mesenchymal stem cells, or cells resembling these cells, have been found in a variety of different tissues in addition to the bone marrow.  These include, fat, menstrual blood and teeth.  One interesting question is how these cells differ from each other.In a recent paper, (Wada et al. Immunomodulatory...
Sunday February 1st, 2009 @ 17:42:33 EST 1 Comment Applauds ISCO

[Watch the Video] Applauds International Stem Cell Corporation (ISCO) On Recent Developments ISCO First To Grow Human Corneal Tissue From Stem Cells, Entering Pre-Clinical Trials For Retinal Disease & Improved Forms of Corrective Laser Eye Surgery January 30,, an organization that covers recent news...
Friday January 30th, 2009 @ 03:44:18 EST

Autologous Adipose for Multiple Sclerosis

[Watch the Video]The use of autologous stem cell therapy has many theoretical and practical advantages.  Autologous bone marrow mononuclear cells were originally used for treatment of ischemic heart failure, and subsequently to prevent post-infarct remodeling.  Numerous other uses of autologous fat derived stem cells have...
Monday January 26th, 2009 @ 00:54:48 EST 1 Comment

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