News Posts
Stem Cells in Davos
[Watch the Video] Youtube made a video contest for best "new ideas" to change the world in 2008. The winning videos will be presented at the World Economic Forum at Davos. The idea here is that the world will be a better place if therapeutic implimentation of autologous bone marrow stem cells are supported by governments and businesses !! If you like the video please pass on to...
Importance of the Injury Signal
Warsaw, Poland - The immune system is activated in response to Danger signals, which evoke various innate molecular pathways that culminate with inflammatory cytokine production and eventual activation of the adaptive immune system. Stem cells circulating in lymphatics have been implicated in recognizing classical danger signals...
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CD133 glycosylated epitope of prominin-1 is marker for pancreatic stem cells
Brussels, Belgium - Numerous tissue have been described to have endogenous, tissue resident, stem cells. For example, cardiac tissues express a population of lineage negative, side population cells that can regenerate myocardium. These cells and their uses are claimed in US patent 7,097,833. The side population phenotype has...
GSK buys into Cancer Stem Cell Vision
London, UK, Philadelphia, PA and Redwood City, CA - It was recently announced that the California venture capital backed company OncoMed has struck a deal with GlaxoSmithKline that could be worth up to 1.5 Billion in milestone payments alone, not counting royalties. Arguably this is one of the highest valued deals for a technology that is still preclinical. In...
Supercharged Mesenchymal Stem Cells
Kobe, Japan - The ability to expand stem cells in culture without their differentiation is one of the features that makes embryonic stem cells attract a lot of attention. For example, in one of the classical WARF patents, the claim is made regarding ability of the embryonic stem cell to proliferate in an...
c-myb needed for smooth muscle differentiation
Ithaca, NY - There is some evidence that bone marrow derived stem cells may transdifferentiate into muscle. In fact, several pieces of evidence suggest that bone marrow stem cells may help to heal injured heart muscle. If stem cells are to be used for generation of muscle...
HSC Transplants...young thymus helps
Osaka, Japan - It is known that as humans grow up their thymus involutes, this is particularly noticable after puberty when various hormones cause en mass death and atrophy of thymic components. Now maybe its just me, but does it not seem odd that hematopoietic stem cell transplants which require the stem cell to differentiate...
Serum Free ES to Hepatocyte Differentiation
Tehran, Iran - The ability to differentiate embryonic stem cells into various tissues would allow for the generation of tailor-made cells that could replenish damaged organs or cells of the organs. If one is to approach this field from the outside, it makes the most sense to start not be trying to build a whole new organ, which is comprised of many cell types, extracellular matrices, and...
TGF-beta stimulating bone marrow to cardiac in vitro
Yamaguchi, Japan - The ability of various mesenchymal stem cell populations and CD34 stem cell populations to help in stimulation of cardiac regeneration is a current belief by many investigators. Although some positive in vivo data have been...
Autologous G-CSF mobilized CD34 for angina
Chicago, IL - The use of stem cells for myocardial repair was originally proposed after mouse studies demonstrated what appeared to be human bone marrow derived stem cells differentiating into myocardium. Subsequently, these experiments were translated into clinical studies, which utilized autologous bone marrow cells as sources...