News Posts
Embryonic Stem Cell Homing
Boston, MA - Administration of bone marrow derived stem cells to patients post-infarct has demonstrated positive clinical results in double blind trials. Additionally, Osiris Therapeutics has reported intravenous administration of allogeneic mesenchymal stem cells increases...Friday February 29th, 2008 @ 15:52:20 EST
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Viral Inflammation Mobilizes Stem Cells
Shanghai, China - It is known that various stem cell types, including mesenchymal and hematopoietic have the ability to home to injured tissue. Mechanisms of homing usually are associated with agents such as stromal derived...Friday February 29th, 2008 @ 14:55:23 EST
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IL-18 in the Heart
Indianapolis, Indiana - It is safe to say that the actual implimentation of stem cell therapy clinically is actually more being performed for purposes of immune modulation than actually growing of new tissues. For example, mesenchymal stem cells are most advanced clinically in the USA by the company Osiris, which are administering mesenchymal stem cells in...Sunday February 17th, 2008 @ 02:36:25 EST
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Acidic mesenchymal stem cells
Los Angeles, CA - Tissue injury is known to cause mobilization of various types of stem cells. For example, after patients have a heart attack, CD34 stem cells, and other types of stem cells are known to mobilize from the bone marrow and enter systemic circulation. Mobilization involvesPancreatic Cancer Stem Cells
Wuhan, China - The concept of cancer stem cells has been around for a while. One could say that initially the concept of cancer stem cells was discovered in the hematopoietic system where the group of Dr Dick from Toronto was able to induce human leukemias in mice with injection of as little as 5-10 cells per mouse. Under normal circumstances if one takes leukemic blasts from patients and...Monday February 4th, 2008 @ 04:39:46 EST
BRCA-1 Involved In Breast Stem Cell Differentiation
Ann Arbor, MI - The concept of a stem cell found within tumor populations that maintains the tumor mass has been around for more than a decade. Patents one using stem cells for screening of new cancer agents have driven the recent GSK-OncoMed deal that in total could be worth approximately $1.5 billion. While it is obvious that...Friday February 1st, 2008 @ 04:03:58 EST
Ex vivo expanded Treg cells protection against allograft rejection
Chicago, IL, USA - Understanding methods of manipulating the immune system to accept allogeneic grafts without the continued need for immune suppression would not only solve the problem of organ transplant rejection but would also bring stem cell therapy (especially embryonic) closer to reality. One interesting method of bringing about such an "immunological tolerance" is through the...Tuesday January 29th, 2008 @ 03:51:17 EST
Breast cancer FGF-2 and VEGF calls in mesenchymal stem cells
Augusta, Georgia - It is believed by many that tissue resident stem cells subsequent to accumulating DNA damage lose proliferative controls and transform into tumors. For example, there is a classical study in which mice were infected with h.pylori and gastric cancer was allowed to develop. Strikingly, the gastric cancer was derived from bone marrow stem cells which had migrated to heal the...Tuesday January 29th, 2008 @ 03:01:42 EST
Velcade guides stem cells to bone
Boston, Massachusetts - Stem cell therapeutics are difficult to commercialize because of the need for cellular manipulation. Even business models that involve off the shelf universal stem cells have the issue that you need are selling an actual biologic product, a product that is very difficult to standardize and ensure quality...Sunday January 27th, 2008 @ 13:23:10 EST
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Stem Cells in Davos
[Watch the Video] Youtube made a video contest for best "new ideas" to change the world in 2008. The winning videos will be presented at the World Economic Forum at Davos. The idea here is that the world will be a better place if therapeutic implimentation of autologous bone marrow stem cells are supported by governments and businesses !! If you like the video please pass on to...Monday January 21st, 2008 @ 14:05:06 EST