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Molecular Mechanisms of Retina Regeneration in Chickens

Oxford, OH - Degeneration of the retina is a significant problem associated with several diseases that cause blindness, such as macular degeneration. In a recent paper (Haynes et al. BMP signaling mediates stem/progenitor cell-induced retina regeneration. Proc Natl Acad Sci U S A. 2007 Dec 14) the investigation of molecular signals associated wtih regeneration of...

Tuesday December 18th, 2007 @ 11:37:32 EST

Tooth stem cells for heart attack

Valencia, Spain - Mesenchymal stem cells have been detected in bone marrow, peripheral blood, muscle and even in menstrual blood. Another...

Monday December 17th, 2007 @ 04:20:06 EST

Bone Marrow Mesenchymal Stem Cells Made to Produce Insulin

Taipei, Taiwan - In addition to their known ability to differentiate into muscle, bone, and neuronal cells, mesenchymal stem cells have been demonstrated to have the ability to differentiate into Monday December 17th, 2007 @ 03:38:27 EST 2 Comments


Immune suppressant stimulating mesenchymal to bone differentiation

Shanghai, China - Mesenchymal stem cells are very useful since they can be administered across allogeneic barriers without need for immune suppression and can be differentiated into various tissues such as liver. In a current paper (Dai et al. Stimulation of osteogenic activity in mesenchymal stem cells by Monday December 17th, 2007 @ 01:12:56 EST


Hepatocyte Growth Factor Helps After Heart Attack

Los Angeles, CA - It is known that mesenchymal stem cells are useful for treating patients after a heart attack. What is however unknown is exactly how these cells mediate their effects. On the one hand mesenchymal stem cells are known to inhibit various inflammatory...


Extending Beta Cell Survival with Exendin-4

Toronto, Canada - Exendin-4 is an agonist of GLP-receptor 1, which is involved in not only increasing the mass of pancreatic beta cells, but has also been implicated in the stimulation of new neuron generation. In addition to exendin-4, agonists of the glucagon-like receptor include various incretin...

Tuesday December 11th, 2007 @ 02:54:12 EST 1 Comment

Mesenchymal stem cells inhibiting cancer

Chengdu, China - The use of mesenchymal stem cells is now a "clinical reality"http://www.stemcellpatents.com/news-show-154, primarily for the treatment of diseases such as multiple sclerosis and other inflammatory conditions. This is due to the known ability of mesenchymal stem cells to differentiate into various tissues, and also...

Monday December 10th, 2007 @ 03:20:53 EST

Generating lung epithelium from cord blood stem cells

Burlington, VT - Generation of lung epithelium de novo would be very useful in the treatment of chronic lung diseases. Unfortunately previous attempts to do this have not been extremely successful. In a recent study (Sueblinvong et al. Derivation of Lung Epithelium From Human Cord Blood-Derived Mesenchymal Stem Cells. Am J Respir Crit Care Med. 2007 Dec 6) human cord blood stem cells...

Monday December 10th, 2007 @ 02:59:41 EST 1 Comment

Hematopoietic Stem Cells Patrolling The Body for Danger

Boston, MA - A potentially new role for stem cells has been described. In most cases, various stem cells such as mesenchymal stem cells as well as hematopoietic stem cells possess immune suppressive characteristics. In a recent publication (Massberg et al...

Wednesday December 5th, 2007 @ 11:20:16 EST

T regulatory cell control of bone resorption

Erlangen, Germany - Although mesenchymal stem cells are primarily known for their differentiation abilities, the first clinical trials, and most likely BLA grantings, will be for immune modulation by these cells in the conditions of graft versus host disease and Crohn's disease. In the same way that Wednesday December 5th, 2007 @ 04:38:55 EST


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