Oxford, OH - Degeneration of the retina is a significant problem associated with several diseases that cause blindness, such as macular degeneration. In a recent paper (Haynes et al. BMP signaling mediates stem/progenitor cell-induced retina regeneration. Proc Natl Acad Sci U S A. 2007 Dec 14) the investigation of molecular signals associated wtih regeneration of...
Valencia, Spain - Mesenchymal stem cells have been detected in bone marrow, peripheral blood, muscle and even in menstrual blood. Another...
Taipei, Taiwan -
In addition to their known ability to differentiate into muscle, bone, and neuronal cells, mesenchymal stem cells have been demonstrated to have the ability to differentiate into
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Shanghai, China -
Mesenchymal stem cells are very useful since they can be administered across allogeneic barriers without need for immune suppression and can be differentiated into various tissues such as liver.
In a current paper (Dai et al. Stimulation of osteogenic activity in mesenchymal stem cells by
Los Angeles, CA -
It is known that mesenchymal stem cells are useful for treating patients after a heart attack. What is however unknown is exactly how these cells mediate their effects. On the one hand mesenchymal stem cells are known to inhibit various inflammatory... Toronto, Canada -
Exendin-4 is an agonist of GLP-receptor 1, which is involved in not only increasing the mass of pancreatic beta cells, but has also been implicated in the stimulation of new neuron generation. In addition to exendin-4, agonists of the glucagon-like receptor include various incretin... Chengdu, China -
The use of mesenchymal stem cells is now a "clinical reality"http://www.stemcellpatents.com/news-show-154, primarily for the treatment of diseases such as multiple sclerosis and other inflammatory conditions. This is due to the known ability of mesenchymal stem cells to differentiate into various tissues, and also... Burlington, VT -
Generation of lung epithelium de novo would be very useful in the treatment of chronic lung diseases. Unfortunately previous attempts to do this have not been extremely successful. In a recent study (Sueblinvong et al. Derivation of Lung Epithelium From Human Cord Blood-Derived Mesenchymal Stem Cells. Am J Respir Crit Care Med. 2007 Dec 6) human cord blood stem cells... Boston, MA -
A potentially new role for stem cells has been described. In most cases, various stem cells such as mesenchymal stem cells as well as hematopoietic stem cells possess immune suppressive characteristics. In a recent publication (Massberg et al... Erlangen, Germany -
Although mesenchymal stem cells are primarily known for their differentiation abilities, the first clinical trials, and most likely BLA grantings, will be for immune modulation by these cells in the conditions of graft versus host disease and Crohn's disease.
In the same way that
Extending Beta Cell Survival with Exendin-4
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Mesenchymal stem cells inhibiting cancer
Generating lung epithelium from cord blood stem cells
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Hematopoietic Stem Cells Patrolling The Body for Danger
T regulatory cell control of bone resorption