News Posts
Liver Failure Regeneration: Its the quality of the injury that matters
Houston, Texas- There are numerous clinical examples of adult stem cells helping people or animals with liver failure. One of the ways in which mesenchymal stem cells help in liver failure is by their ability to produce IL-10 in response to stellate cell generated IL-6, and...
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Treg cells causing "alternative activation" of monocytes
London, UK - In immunology, the notion that T cells are activated by antigen presenting cells has been around for decades. At one time, it was believed that T cells are activated by "immune RNA" generated from antigen presenting cells, this immune RNA being able to "instruct" the T cell to go after specific antigens. Afterwards, the major...
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PSGL-1 and generation of tolerogenic dendritic cells
Madrid, Spain - The advancement of allogeneic stem cell research into the clinic has always been dependent on immunology. In other words, allogeneic stem cell therapy is dependent on ability of the clinician to manipulate the recipient immune system so that the allogeneic cells do not get rejected (host versus graft), nor that the recipient gets attacked by the cells administered (graft...
Bone marrow stem cells in pulmonary hypertension
New Orleans, Louisiana - Adult stem cells have been used clinically in treatment of heart failure, liver failure, and advanced peripheral artery disease. One exciting possible use of stem cells is in the treatment of...
A New Age in Regenerative Medicine
Kyoto, Japan -
In a recent paper Takahashi K et al. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors.Cell. 2007 Nov 20 generation of an "inducible pluripotent stem cell" or iPS from human skin was announced.
Here is a video... [Watch the Video]
This is a video describing the recent paper in Cell in which skin fibroblasts were retrodifferentiated to cells that "looked and felt" like embryonic stem cells. This is a major breakthrough in our knowledge of cell dedifferentiation and ability to use distinct, chemically-defined factors to coax an old cell into becoming a young cell again. Frederick, Maryland -
Although mesenchymal stem cells are currently used in an allogeneic manner clinically, the question of whether they are truly tolerogenic is still debated. Other stem cell types such as CD34 or embryonic stem cells may... Cincinnati, OH -
Commercialization of stem cell therapy is difficult since sometimes one doesn't really know what the product is. Additionally, there could be many products that are developed that are used in the implimentation of a single therapy.
A current publication (Pasha et al. Preconditioning Enhances Cell Survival and Differentiation of Stem Cells during Transplantation in... Medistem Announces Discovery of Novel Stem Cell Population in Menstrual Blood: Endometrial Regenerative Cells (ERC) Cells Produce 100,000 Times the Number of Growth Factors Found in Cord Blood
SCOTTSDALE, AZ--(Marketwire - November 15, 2007) - Medistem Laboratories, Inc. (OTCBB: MDSM) (FRANKFURT: S2U) in... [Watch the Video]
This is one of many newsclips describing the discovery of pluripotent stem cells from the menstrual blood in a recent publication by the adult stem cell company Medistem (mdsm.ob).
Embryonic Stem Cells from Skin
Rapamycin turns stops Th17 but promotes Treg
Giving stem cells a kick in vitro with stromal derived factor-1
Medistem Publishes Menstrual Stem Cell Discovery
Medistem (mdsm.ob) Discovers Menstrual Blood Stem Cells