Class: Use (247)
Isolated stromal cells for use in the treatment of diseases of the central nervous system
Patent Number: 6653134This patent teaches that one can induce the differentiation of stromal stem cells into neural cells, through the culture of the stromal cells with differentiated neural cells. This patent is useful not only for generating cells for treatment of neurological conditions, but also may be used to begin elucidating what the specific signals are that the neural cells use to teach the stromal stem...
Cell-based gene therapy for the pulmonary system
Patent Number: 6482406This patent covers the transfection of various cells and their administration in order to heal various pulmonary lesions or disorders. In one utilization, cells are transfected with iNOS and used to administer nitric oxide directly into the lung of patients with pulmonary hypertension.
Implant for repairing cartilage having outer surface layers of copolymer and ceramic material
Patent Number: 6737073This is an implantable matrix that can be used for growing stem cells in vitro for the regeneration of cartilage. The implant has several advantages over the prior art including the fact that it is compartamentalized in structure to provide a more "in vivo" like function.
Methods and compositions for healing and repair of articular cartilage
Patent Number: 7,323,445This patent covers the regeneration of articular cartilage by administering an osteochondral graft together with purified bone morphogenetic protein (BMP) selected from the group consisting of BMP-2, 4, 5, 6, and 7 and one protein which induces the formation of tendon or ligament tissue selected from the group consisting of BMP-12,
Methods and compositions for healing and repair of articular cartilage
Patent Number: 6727224This patent teaches the use of bone morphogenic proteins together with stem cells for repair of articular cartilage injury. In some embodiments the stem cells may be endogenous.
Method of evaluating myelosuppressive state
Patent Number: 7,279,289In the spirit of Labcorp v Metabolite this patent covers methods of assessing a phenomena and based on this assessment intervening appropriately. If you read the case you will see where we are going with this. The patent covers the monitoring of various hematopoietic cytokines in order to assess myelosuppression...
Method of evaluating myelosuppressive state
Patent Number: 6649352After chemotherapy or radiation therapy, the myeloid compartment of the immune response is suppressed, due to destruction of the myeloid stem cell compartment. This patent provides a kit that allows the determination of myelosuppression, and therefore can be used to guide the amount of myelo-stimulatory therapy (ie G-CSF) that should be administered. The kit measures alone or in combination...
Methods for reducing adverse side effects associated with cellular transplantation
Patent Number: 6387366This patent teaches ways how to overcome some of the negative effects associated with cell therapy in regards to excessive coagulation. It is stated in the specification that in many cases the administration of a cellular therapy results in coagulation of blood due to expression of pro-clotting agents on the surface of the administered blood cells such as tissue factor. The patent teaches...
Bone resorption inhibitors
Patent Number: 6723696This patent covers a novel factor that on the one hand is involved in leukocyte activation, and on the other hand inhibits bone resorption. This factor is useful in conjunction with stem cell therapies that stimulate bone formation.
Assessing the condition of a joint and devising treatment
Patent Number: 7,239,908In stem cell therapy it is not only important to have the right types of stem cells, but it is just as important to know the proper indication and stage of the progression of the indication when intervention is most likely to yeild benefit. This is what the current patent is covering in the area of joint degeneration.
The patent covers very interesting methodologies for convering
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