Myocardial infarctions cause massive lose of cardiac muscle, as well as cause numerous electrophysiological dysfunctions that can immediately or in the long-term lead to death. The current patent has 2 independent claims that deal with this. The first one teaches the application of a pacing therapy in the infarct area together with the percutaneous administration of porcine "donor...
This patent covers a type of stent that contains cells and is useful not only for maintaining open a blood vessel, but also for delivery of cells that secrete various agents useful for the body. The patent has two independent claims, the first covering a stent containing cells, the second covering a method of administering cells into an organism. Stents have been covered with many agents in...
This patent covers a device that stimulates conductivity of electrical signals in the heart. Amongst the uses of the invention is to ensure proper biventricular septal pacing. The invention claims the use of various cells, including stem cells, for increasing certain conductivity connections.
Although the patent describes a keratinocyte population, the fact that the cells claimed can proliferate past the Hayflick limit, stimulated us to discuss this patent. The use of allogeneic cells for covering burns and other types of wounds has been widely known in the art, however in the current patent a type of keratinocyte with immense proliferative potential is described. The patent...
Based on the title, one would think that this patent covers global use of PCR amplifying for CD133 transcripts in order to detect angiogenic propensity in a host. If this were the case, then the patent indeed would be very strong.
The patent, however, is restricted to covering the diagnosis of colorectal cancer using PCR... This patent covers methods of making genetically engineered pigs. This is an important area of study not only from a research perspective, but also that transgenic animals may be used for things such as: a) mass production of proteins; b) donor organs for humans; and c) agricultural purposes. The patent teaches the generation of pigs by: 1. Obtaining a pig ES cell... It is known that various hematopoietic cells are involved in the ocular injury caused by uncontrolled angiogenesis. This occurs, for example, in wet macular degeneration, a disease in which antiangiogeneic agents are clinically used successfully. Since hematopoietic lineage cells are known to enter the ocular areas and assist in angiogenesis, the inventors asked why not use these cells as a... This patent covers the inhibition of placental growth factor as a method of treating osteoporosis. The one issued claim is restricted to inhibition of placental growth factor using an antibody or fragments of the antibody. The inventor demonstrated inhibition of bone resorption in an animal model, as well as in vitro using anti-placental growth factor antibodies... One may notice that many of the patents in the StemCellPatents.com database direct their claims towards "mammals" here is one exception. The current patent is directed towards cloning of fish. The inventors state that nuclear transfer in fish was actually performed since the 1960s, however despite much work in the area, this is the first time that cultured cells are used as nucleus donors... Trangenic animals have been very useful in the basic sciences in terms of elucidating biological activities of specific proteins in an in vivo situation. In terms of developing therapeutics, transgenic animals are useful for a wide variety of practical purposes ranging from in vivo production of recombinant proteins for human use, to serving as bioincubators for tissue and three-dimensional...
Nuclear transfer with porcine embryonic stem cells
Patent Number: 7,371,922
Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
Patent Number: 7,153,501
Placental growth factor as a target for the treatment of osteoporosis
Patent Number: 7,357,929
1 Comment
Fish produced by nuclear transfer from cultured cells
Patent Number: 7,332,647
Chimeric bird from embryonic stem cells
Patent Number: 7,145,057
1 Comment