Class: Use (242)
Autogenous cell patch cardio myoplasty and advanced muscle graft implantation system
Patent Number: 6435190This patent teaches what appears to be a surgical method for producing an autograft that can cover lesions in the heart. This is important since after a heart attack, there is scar tissue formation, and the heart starts to lose function. The patent also covers ways in which autologous stem cells may be administered.
Gene expression analysis of pluri-differentiated mesenchymal progenitor cells and methods for diagnosing a leukemic disease state
Patent Number: 7049072It is known from the literature that the non-tumor stroma surrounding the tumor plays an important role in the growth of the tumor by facilitating angiogenesis, providing growth factors, etc. In hematological malignancies, the fact that donor-derived leukemic relapse occurs in some individuals suggests that stromal elements may be responsible, or associated with leukemic transformation...
Surface modifications for enhanced epithelialization
Patent Number: 6689165This patent teaches how to accelerate healing of epithelial cells of the cornea through administration of an optical polymer that consists, in part of a hydrogel. The devices and compositions thought are useful for stimulation of stem cells associated with production of corneal epithelial cells.
Neuroprotective peptides
Patent Number: 7,259,146This patent covers specific peptides derived from erythropoietin, as well as from other molecules, that have ability to increase neurite outgrowth in cell culture. Specifically, the claims appear to be restricted only to a method of increasing neurite outgrowth in cell culture. The neuroprotective roles of erythropoietin have been known for many years and have been assessed and are being...
Microinjection of cryoprotectants for preservation of cells
Patent Number: 7094601This patent is useful for cryopreservation of extremely sensitive cells such as oocytes and stem cells. Particularly, the patent deals with microinjection of various agents that protect cells during cryopreservation. The patent has 2 independent claims. The first covers the culture of oocytes (the concept that "culture" will be frozen) such that a cryopreservation agent is injected...
Conditioned cell culture medium compositions and methods of use
Patent Number: 7,118,746This patent covers protection of keratinocytes from a variety of stresses by administration of conditioned media from a variety of stem cell sources. This patent is useful for cosmetics and also for skin regeneration.
Treatment of disorders by implanting stem cells and/or progeny thereof into gastrointestinal organs
Patent Number: 6808702This patent is very interesting in that it provides a source of nitric oxide through the use of fetal and embryonically derived neural stem cells. The neural stem cells can be administered by various means in order to correct gastrointestinal deficiencies.
Methods and compositions for treating intervertebral disc degeneration
Patent Number: 6723335This patent covers the use of a fluid matrix together with stem cells, specifically mesenchymal stem cells, for the regeneration of the nucleus pulposus. This invention is suitable for treatment of patients with lower back pain due to disc degeneration.
Growth factor therapy mobilization of stem cells into the peripheral blood
Patent Number: 7,291,597This patent covers the use of inhalation therapy of cytokines (FGF-1,2 and VEGF) for mobilization of stem cells. The patent is similar to patent 7,288,521 which was discussed last week.
Cardiac valve replacement
Patent Number: 6652583This patent teaches how to use stem cells and other differentiated cells in order to generate a heart valve that can be used for replacement of defective valves in patients suffering from various valvular abnormalities. The advantage of this biological valve is that it conceptually is longer lasting than completely artificial or xenogeneic valves.