Class: Use (242)
Method for in vivo ex vivo and in vitro repair and regeneration of cartilage and collagen and bone remodeling
Patent Number: 6528052This patent discloses frequencies and methods of culturing stem cells in order to generate a source of bioartificial cartilage.
Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
Patent Number: 7078232Repair of articular cartilage is a substantial problem. The patent is useful for entities interested in providing a solution to this problem through the administration of cellular therapy containing adipose-derived stem cells in a biocompatible matrix or delivery system. The patent specifically has 4 independent claims. The first claim covers a composition of matter that is useful for...
Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
Patent Number: 7033587This patent teaches ways to make artificial cartilage patches using adipose stem cells as starting material. These patches may be useful for people having injuries in which cartilage is damaged. The patent has 1 independent claim which essentially covers producing such an artifical patch through taking out adipose stem cells, culturing the cells to become chondrocytes, allowing the...
Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
Patent Number: 6841150This appears to be a very important patent in that it teaches the use of adipose stem cells for generating chondrocytes and using the chondrocytes to heal cartilage. This patent should be compared to ones by Osiris that use adipose derived mesenchymal stem cells for cartilage repair, as well as by Cytori which uses adipose derived stem cells for a variety of indications.
Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
Patent Number: 6429013This patent teaches how to generate cartilage and chondrocytes from stromal cells that are derived from adipose tissues. Another company working heavily in this area is Cytori, formerly called Macropore.
Treatment of liver disease and injury with CXC chemokines
Patent Number: 6719969This patent teaches that CXC chemokines are potent stimulators of hepatic stem cells and hepatic regeneration. Chemokines covered include MIP-2, ENA-78 and IL-8.
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Muscle cells and their use in cardiac repair
Patent Number: 6673604This is a composition patent covering myocardial and fibroblast cell preparations that are useful for administration in the post-infarct myocardium. This approach is interesting and a similar approach seems to have been used clinically by the company Bioheart.
Ischemia detection system
Patent Number: 6277082This patent provides a medical device that detects ischemia based on electrical conductivity and other parameters. This invention is useful in combination with stem cell therapy so as to enable the administrator of stem cell angiogenic therapy to decide when and where therapy is needed.
Hematopoietic cell composition for use in transplantation
Patent Number: 7101708This patent is useful for parties looking to increase bone marrow stem cell homing to areas of need. In normal bone marrow transplants, stem cells from the donor are introduced intravenously and find their way to the bone marrow by virtue of bone marrow-secreted stromal derived factor-1 (SDF-1). It was more recently discovered that following tissue injury (for example stroke and myocardial...
Devices and methods for treating tissue
Patent Number: 6719805This patent seems to cover the use of angiogenic stimuli, together with stem cells for treatment of muscle disorders including disorders associated with the myocardium. This patent may influence the current trials ongoing for treatment of myocardial dysfunction with stem cells and angiogenic stimuli.