Class: Extraction/Preservation (153)
Stem cell factor receptor-(c-kit)-specific monoclonal antibody A3C6E2
Patent Number: 5808002This patent covers the use of an antibody to c-kit for the quantification and extraction of hematopoietic stem cells. Since non-hematopoietic stem cells also express c-kit, this antibody may have other uses than originally contemplated.
Human stem cell antigen 2
Patent Number: 6130061This patent covers a new protein that is expressed on various types of stem cells. This protein can be used for purification of stem cells from tissue, or for assessment of stem cell populations in various in vitro culture systems.
Methods for preparing enriched human hematopoietic cell preparations
Patent Number: 6306575This patent provides kits for negatively depleting a population of cells so that what remains is hematopoietic stem cells. Different variants of this kit are sold by the Canadian company StemCell Technologies.
Methods of obtaining compositions enriched for hematopoietic stem cells, antibodies for use therein, compositions derived therefrom and methods of use thereof
Patent Number: 6127135This patent covers a novel marker of stem cells which the inventors call EM10. This patent is useful for identifying the stem cell content of a population of cells.
Myocardial grafts and cellular compositions
Patent Number: 6015671This patent teaches how to extract specific cells from a population of stem cells that are differentiating.
Methods of obtaining compositions enriched for hematopoietic stem cells, antibodies for use therein, compositions derived therefrom and methods of use thereof
Patent Number: 5814440Disclosed are methods of purifying hematopoietic stem cells using the antibody EM10.
Method of preparing hematopoietic stem cells with gp105-specific antibodies
Patent Number: 6083747This patent discloses a new marker of hematopoietic stem cells. The marker can be used for isolation, purification, or identification of such stem cells.
Identification of blast cells in a leukocyte cell preparation
Patent Number: 5905031This patent covers ways of detecting blast cells from other types of cells using photometric means.
Isolated stromal cells and methods of using the same
Patent Number: 6974571The invention covers a way of introducing stem cells into a host in such a manner that the cells can be killed off if desired through administration of an agent that induces expression of a suicide gene. This is important since in some situations it is desired to have the exogenous stem cells in the body only for a limited period of time. Specifically, the invention has 2 independent claims...
FGFR3 as a marker for mesenchymal skeletal progenitor cells
Patent Number: 6517872This patent teaches ways of extracting mesenchymal stem cells that act as progenitors for various types of bone. The expression of the receptor for fibroblast growth factor-3 is used as the identifying marker.