Class: Extraction/Preservation (151)
Method to produce novel embryonic cell populations
Patent Number: 6110739This patent covers generation of cells from embryonic stem cells, and subsequent immortalization of the generated cells. The generated cells may be semidifferentiated stem cells or precursor cells. Immortalization may be accomplished by transfection with the gene HOX 11.
Methods of obtaining compositions enriched for hematopoietic stem cells, compositions derived therefrom and methods of use thereof
Patent Number: 5677136This patent teaches that the protein CD59 may be used as a marker of hematopoietic stem cells both for identification, and also for purification.
Method of purifying a population of cells enriched for hematopoietic stem cells populations of cells obtained thereby and methods of use thereof
Patent Number: 5665557This patent covers the use of CDw109 for purification and identification of hematopoietic stem cells.
Neural cell protein marker RR/B and DNA encoding the same
Patent Number: 6066451This patent provides a marker for the identification of specific neural cells. This marker is useful for knowing the quantity and quality of neurons generated from various stem cell populations.
Method of selecting pluripotent hematopioetic progenitor cells
Patent Number: 5827742This patent takes advantage of the fact that early hematopoietic stem cells are usually CD34+ and quiescent. By treatment of CD34+ cells with cytotoxic agents that kill proliferating cells, a population of primitive stem cells may be obtained.
Isolation, selection and propagation of animal transgenic stem cells
Patent Number: 6878542This patent appears to be a really unique way of expanding stem cells. Essentially the patent teaches to connect a growth factor receptor to a promoter that is only expressed on stem cells, such as the promoter for Oct-4. This way stem cells will express the growth factor receptor. This way if you add the ligand for the receptor the stem cells will proliferate...
Method of enriching for mammalian stem cells
Patent Number: 6146888In this patent an antibiotic resistance gene is placed under the control of a promoter associated with stem cells. This way only the stem cells will live while the other cells will die when exposed to the antibiotic.
Myocardial grafts and cellular compositions useful for same
Patent Number: 6399300This patent teaches ways of purifying out cells expressing myocardial genes from a heterogeneous population of stem cells. Specifically the patent teaches the use of cardiac specific promoters driving expression of markers that can be used to take the cells desired out of a heterogeneous population of cells.
In vitro method for producing differentiated universally compatible human blood cells
Patent Number: 5811301This patent teaches ways of genetically modifying stem cells, and their progeny so as to generate a population of cells that is acceptable by all humanity.
Method to distinguish hematopoietic progenitor cells
Patent Number: 6555324This patent covers methods for identifying hematopoietic stem cells based on expression of markers such as CD34, CD38, and various growth factor receptors.