Patents (1343 Stem Cell Patents)

Class: Extraction/Preservation (150)

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Apparatus for removing fluid from an umbilical cord

Patent Number: 5171527

This patent provides a medical device for rapidly extracting cord blood from an umbilical cord. This may be useful for collection of cord blood stem cells, which is a common practice in current medicine.

Inventors: Knippscheer, Hermann (Baldwin, NY); Richard, Daniel D. (Sedona, AZ)
Assignee: Cryo-Cell International, Inc. (Baldwin, NY)
Date of First Priority Issue: Friday January 26th, 1990

Generation of neural precursor cell lines

Patent Number: 5580777

This patent covers neural stem cells that have been immortalized with c-myc or n-myc. These cells are useful not only for in vitro study and drug discovery, but also for therapy if differentiated properly so as to not possess malignant potential. The owner of the patent, Amrad, possesses numerous powerful patents in the area of stem cells.

Inventors: Bernard, Ora (North Balwyn, AU); Bartlett, Perry F. (North Carlton, AU)
Assignee: Amrad Corporation Limited (AU)
Date of First Priority Issue: Wednesday December 28th, 1988

Derivation of pluripotential embryonic cell lines from ungulate species

Patent Number: 6436701

This patent covers methods of generating stem cells, embryonic stem cells from ungulate species. This technology may be useful not only for veterinary applications, but also for generating large quantities of cytoplasm with "dedifferentiating" ability that may be used for various regenerative purposes in humans...many of the cytoplasmic factors in embryonic stem cells that induce...

Inventors: Evans, Martin John (Cambridge, GB); Moor, Robert Michael (Babraham, GB); Notaranni, Elena (Cambridge, GB)
Assignee: Babraham Institute (Cambridge, GB)
Date of First Priority Issue: Monday September 12th, 1988

Method of freezing cells and cell-like materials

Patent Number: 6007978

This patent covers methods of freeze-drying various cells, including stem cells.

Inventors: Goodrich, Jr., Raymond P. (Pasadena, CA); Coker, Samuel O. S. (South Pasadena, CA); Arnaud, Francoise (Pasadena, CA); Hackett, Roger W. (Pasadena, CA)
Assignee: COBE Laboratories, Inc. (Lakewood, CO)
Date of First Priority Issue: Wednesday May 18th, 1988

Human stem cells and monoclonal antibodies

Patent Number: 4965204

This patent is a division of application Ser.No. 670,740, filed Feb.6, 1984 which issued on Dec. 22, 1987 as U.S. Pat. No. 4,714,680 and was described below. This patent is similar to 4,714,680 with the exception that the one independent claim in this patent covers in more detail the antibody which is now known to recognize CD34. Inventor: Civin, Curt I. (Baltimore, MD)

Assignee: The Johns Hopkins University (Baltimore, MD)
Date of First Priority Issue: Tuesday December 22nd, 1987

Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood

Patent Number: 5004681

This patent covers freezing of cord blood for future use. The patent has one independent claim covering the composition of a cryopreservant, together with viable fetal or neonatal hematopoietic cells. PharmaStem is the successor to Biocyte Corporation, the assignee of this patent. This patent, together with patents 5 192 553, 6 461 645, 6 569 427 and 6 605 275 are used by Pharmastem to...

Inventors: Boyse, Edward A. (New York, NY); Broxmeyer, Hal E. (Indianapolis, IN); Douglas, Gordon W. (New York, NY)
Assignee: Biocyte Corporation (New York, NY)
Date of First Priority Issue: Friday December 11th, 1987

Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood

Patent Number: 6605275

This patent covers preservation of cord blood cells. It is one of the patents that is actually generating revenue and has stood the test of litigation. Anyone doing cord blood banking in the US has to license this patent.

Inventors: Boyse, Edward A. (Tucson, AZ); Broxmeyer, Hal E. (Indianapolis, IN); Douglas, Gordon W. (New York, NY)
Assignee: PharmaStem Therapeutics, Inc. (Wayne, PA)
Date of First Priority Issue: Thursday November 12th, 1987

Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood

Patent Number: 6569427

This patent covers the use of cord blood cells. Any cord blood bank in the US has to license this patent or else Pharmastem will litigate as they have in the past.

Inventors: Boyse, Edward A. (Tucson, AZ); Broxmeyer, Hal E. (Indianapolis, IN); Douglas, Gordon W. (New York, NY)
Assignee: PharmaStem Therapeutics, Inc. (Del Mar, CA)
Date of First Priority Issue: Thursday November 12th, 1987

Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood and methods of therapeutic use

Patent Number: 5192553

This is a patent on freezing cord blood stem cells. This is an important patent since it is generating revenue. The company Pharmastem used this patent and several others in order to position itself in the cord blood industry. Additionally, this patent stood the test of litigation.

Inventors: Boyse, Edward A. (Tucson, AZ); Broxmeyer, Hal E. (Indianapolis, IN); Douglas, Gordon W. (New York, NY)
Assignee: Biocyte Corporation (New York, NY)
Date of First Priority Issue: Thursday November 12th, 1987

Composition and method for supporting bone marrow transplantation

Patent Number: 5186931

This patent provides a composition of cytokines for stimulating hematopoiesis after a bone marrow transplant, as well as for the in vitro stimulation of hematopoiesis. The composition involves B cell differentiation factor and some commonly used cytokines today.

Inventors: Kishimoto, Tadamitsu (Nakano Tondabayashi-shi, Oosaka-fu, JP); Hirano, Toshio (Ibaraki, JP); Akiyama, Yukio (Kawasaki, JP); Okano, Akira (Kawasaki, JP); Matsui, Hiroshi (Kawasaki, JP); Takahara, Yoshiyuki (Kawasaki, JP)
Assignee: Ajinomoto Co., Inc. (Tokyo, JP) Kishimoto, Tadamitsu (Tondabayashi, JP)
Date of First Priority Issue: Wednesday August 6th, 1986

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