Class: Extraction/Preservation (149)
System and method for processing bone marrow
Patent Number: 7008394Bone marrow transplants, as well as other bone marrow applications represent by far the largest use of stem cells in medicine. The process of harvesting bone marrow may be complicated and prone to contamination. Since bone marrow harvest is a painful and almost traumatic procedure, contamination of a bone marrow graft during harvest could be disasterous. The current invention teaches the use...
Method of isolating human neuroepithelial precursor cells from human fetal tissue
Patent Number: 6852532This patent teaches methods of extracting and purifying neuroepithelial precursor cells that can differentiate into a variety of neurological tissue and be useful for regenerative medicine. The patent essentially teaches to deplete cells expressing the markers A2B5, NG2 and eNCAM, so that approximately half of the purified cells are positive for
Method for producing a population of homozygous stem cells having a pre-selected immunotype and/or genotype, cells suitable for transplant derived therefrom, and materials and methods using same
Patent Number: 7030292This invention teaches how to generate a "cell bank" of embryonic stem cells that are homozygous at HLA. Theoretically, the inventors suggest..."that a few hundred stem cell lines that are homozygous for different haplotypes will be sufficient to match a majority of the human population. This number is tremendously smaller in contrast to the number of...
Cell surface expressed marker of pluripotency
Patent Number: 7,226,994This patent covers the composition of matter for two markers that are widely used for detecting germ cells. The markers being Fragilis and Stella. These are found also in embryonic stem cells and primordial germ cells. The patent is useful for development of laboratory reagents, as well as clinically developing methods of isolating specific cell populations.
Isolating cells expressing secreted proteins
Patent Number: 6919183This patent teaches ways of extracting cells from a population based on expression of markers that were either introduced or naturally expressed in the cell. The patent may be useful for pulling out differentiated cells from stem cell heterogenous populations. A method of detecting and/or isolating a eukaryotic cell that produces a secreted protein of interest (POI), comprising: (a...
Container for biological products requiring cellular stasis
Patent Number: 6773425This patent discloses various vessels and uses thereof that can be used to store stem cells and other biological products during transportation.
Method of concentrating and separating dopaminergic neurons
Patent Number: 7,270,998Selection of cells with specific phenotypes is a critical part of the development of stem cell therapeutics. Several patents are issued on methods of selecting differentiated cells with a specific phenotype from a heterogenous population. In the current patent 5 independent claims are issued covering the isolation of dopamine producing cells by the selection of cells which have an active...
Method of identifying a neural progenitor cell by evaluating expression of daedalos
Patent Number: 6759201This patent covers a new marker for neural stem cells called Daedalos. It provides methods of using this marker for identifying and extracting neural stem cells. The neural stem cells can be used for treatment of a variety of neurological disorders such as Parkinsons, Alzheimers, etc.
Devices and methods for harvesting limbal stem cells
Patent Number: 6679898This patent provides a medical device and ways to use the device to extract corneal tissue and limbal stem cells from the eye of a donor.
Compositions for identification and isolation of stem cells
Patent Number: 6632620This patent provides an antibody that recognizes both epidermal stem cells, as well as prostate cancer cells.