Class: Extraction/Preservation (153)
Propagation and/or derivation of embryonic stem cells
Patent Number: 6875608This patent discloses compounds that can be added to a culture of embryonic stem cells so as to selectively kill non-embryonic stem cells.
Antibody composition for isolating human cells from human-murine chimeric hematopoietic cell suspensions
Patent Number: 6342344This patent provides kits for purifying out of a human-SCID mouse cells of human origin.
Method of isolating stem cells
Patent Number: 6991897This and patent #5,876,956 are licensed to the company Aldagen (2810 Meridian Parkway Suite 148 Durham, NC 27713 919-484-2571) that is actually purifying stem cells using this method for clinical trials (for example: Intramyocardial Injection of Autologous Aldehyde Dehydrogenase-Bright Stem Cells for Therapeutic Angiogenesis at Texas Heart: Oct 5, 2006). The patent covers purifying stem...
Methods for storing neural cells
Patent Number: 6821779This patent covers methods of storing neural stem cells and neural cells that have been differentiated from stem cells. This patent covers not only human but also porcine cells. The assignee company was at one time performing clinical trials with encapsulated porcine neural cells in patients.
Methods for storing neural cells such that they are suitable for transplantation
Patent Number: 6713245This patent covers methods of preserving neural stem cells and various types of neuronal cells so that they may be transported for use in treatment of neurological disorders. One of the drawbacks of such cell therapy is the issue of rejection by the allogeneic immune system, this has been addressed in studies using encapsulation, or using stereotactic implantation into the brain, since the...
Relationship of ABC transport proteins with hematopoietic stem cells and methods of use thereof
Patent Number: 6933150This patent seems to cover methods of purifying and expanding hematopoietic stem cells by transfecting said stem cells with a drug efflux pump. It is not clear if the patent calls for administration of a cytotoxic agent to selectively kill non-stem cells, or if it is inherently the property of the efflux pumps to increase stem cell viability. The patent has 2 independent...
Systems for processing and storing placenta/umbilical cord blood
Patent Number: 6059968Methods and devices are disclosed that enable efficient collection and storage of cord blood.
Purging of stem cell products
Patent Number: 6475481This patent covers ways of purging tumor cells from bone marrow stem cell grafts. Specifically, the patent teachs ways of selectively protecting the bone marrow through gene transfection, while allowing tumor cells to die. This patent is particularly suited for situations of autolous bone marrow transplants in cancer patients in order to allow for high levels of chemotherapy and/or...
Transfection, storage and transfer of male germ cells for generation of transgenic species and genetic therapies
Patent Number: 6734338This patent teaches how to transfect male germ stem cells in non-human mammals. This technology is useful for generation of a variety of animal models for laboratory experimentation. It is also useful for research companies who want to circumvent some of the transgenic patents today.
Cell separation using electric fields
Patent Number: 6589786This patent teaches how to utilize distinct electromagnetic properties of stem cells for their isolation. Additionally it teaches how to purge a population of stem cells from contaminating cancer cells.