Usually bone marrow is extracted from the iliac crest of patients. In this patent a new device for extracting bone marrow is disclosed. The patent is useful for, intra alia, taking out bone marrow from the jaw bone of a subject that is undergoing dental surgery. If you thought root canals are painful, imagine this !
This patent provides procedures and devices useful for harvesting bone marrow. In one embodiment the bone marrow is harvested from the jaw of the patient.
This patent teaches methods and discloses devices, that are useful for the extraction of bone marrow stem cells from the jawbone of a patient.
This patent is directed to the stimulation of hematopoietic stem cell proliferation by use of a lectin called FRIL. The patent has 2 independent claims. The first is directed towards a pharmaceutical composition claiming some distinct sequences that bind glycosylated flt-3. The second is directed towards treatment, using the same sequences. There is a paper...
This patent teaches that certain lectins (sugar binding proteins) may be used for the preservation of progenitor cells and stem cells. It is not clear which property of the lectins is involved in the preservation. The concept that lectins may be used in stem cell preservation brings to mind old experiments in which the preferentially affinity of lectins to cancer cell membranes was...
This patent covers the use of NGF for storing corneal samples, but also for use as a topical solution for the treatment of diseases associated with corneal dysfunction.
This patent claims that expression of the anti-apoptotic gene bcl-2 can be used as a marker for stem cells of the muscle. The problem is that bcl-2 is an intracellular molecule, therefore it is difficult to selectively purify based on its expression. If a colourogenic substrate for bcl-2 can be discovered or already exists, this would greatly increase the value of the current patent.
This patent provides devices that can quantify hematopoietic stem cell numbers from a pool of cells through non-immunological means.
This patent appears to cover a new method of detecting hematopoietic stem cells, without needing to use stem cell-specific markers. The patent seems to use some light and physical properties of the cells to distinguish between stem cells and non-stem cells. The patent has one issued claim which is: "A method for detecting or counting or both detecting and counting hematopoietic...
This patent covers peptides that inhibit hematopoietic stem cell proliferation, thereby allowing protection of these cells from chemotherapy or radiotherapy. This patent may conceptually be applicable to selectively inhibiting healthy stem cells while allowing leukemic stem cells to proliferate so that chemotherapy or radiotherapy may selectively kill the proliferating leukemic cells.