Patents (1354 Stem Cell Patents)

Class: Extraction/Preservation (151)

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Apparatus for extracting bone marrow

Patent Number: 6358252

Usually bone marrow is extracted from the iliac crest of patients. In this patent a new device for extracting bone marrow is disclosed. The patent is useful for, intra alia, taking out bone marrow from the jaw bone of a subject that is undergoing dental surgery. If you thought root canals are painful, imagine this !

Inventor: Shapira, Ira L. (Highland Park, IL)
Assignee: None stated
Date of First Priority Issue: Tuesday July 1st, 1997

Methods for extracting bone marrow

Patent Number: 6110176

This patent provides procedures and devices useful for harvesting bone marrow. In one embodiment the bone marrow is harvested from the jaw of the patient.

Inventor: Shapira, Ira L. (Highland Park, IL)
Assignee: not stated
Date of First Priority Issue: Tuesday July 1st, 1997

Apparatus for extracting bone marrow

Patent Number: 5913859

This patent teaches methods and discloses devices, that are useful for the extraction of bone marrow stem cells from the jawbone of a patient.

Inventor: Shapira, Ira L. (Highland Park, IL)
Assignee: None Stated
Date of First Priority Issue: Tuesday July 1st, 1997

Progenitor cell preservation factors and methods for and products of their use

Patent Number: 6991794

This patent is directed to the stimulation of hematopoietic stem cell proliferation by use of a lectin called FRIL. The patent has 2 independent claims. The first is directed towards a pharmaceutical composition claiming some distinct sequences that bind glycosylated flt-3. The second is directed towards treatment, using the same sequences. There is a paper...

Inventors: Colucci, M. Gabriella (La Jolla, CA); Chrispeels, Maarten J. (La Jolla, CA); Moore, Jeffrey G. (Kennebunkport, ME)
Assignee: ImClone Systems Incorporated (New York, NY) The Regents of the University of California (La Jolla, CA)
Date of First Priority Issue: Tuesday June 24th, 1997

Lectin-derived progenitor cell preservation factor and methods of use

Patent Number: 6852321

This patent teaches that certain lectins (sugar binding proteins) may be used for the preservation of progenitor cells and stem cells. It is not clear which property of the lectins is involved in the preservation. The concept that lectins may be used in stem cell preservation brings to mind old experiments in which the preferentially affinity of lectins to cancer cell membranes was...

Inventors: Colucci, M. Gabriella (Dugenta, IT); Chrispeels, Maarten J. (La Jolla, CA); Moore, Jeffrey G. (Kennebunkport, ME)
Assignee: ImClone Systems Incorporated (New York, NY) Regents of the University of California (La Jolla, CA)
Date of First Priority Issue: Tuesday June 24th, 1997

Use of nerve growth factor for the storage, culture or treatment of cornea

Patent Number: 6537808

This patent covers the use of NGF for storing corneal samples, but also for use as a topical solution for the treatment of diseases associated with corneal dysfunction.

Inventor: Lambiase, Alessandro (Rome, IT)
Assignee: Anabasis S.R.L. (Rome, IT)
Date of First Priority Issue: Thursday April 24th, 1997

Molecular marker for muscle stem cells

Patent Number: 6337184

This patent claims that expression of the anti-apoptotic gene bcl-2 can be used as a marker for stem cells of the muscle. The problem is that bcl-2 is an intracellular molecule, therefore it is difficult to selectively purify based on its expression. If a colourogenic substrate for bcl-2 can be discovered or already exists, this would greatly increase the value of the current patent.

Inventor: Miller, Jeffrey B. (Cambridge, MA)
Assignee: None stated
Date of First Priority Issue: Tuesday April 1st, 1997

Method of detecting hematopoietic progenitor cells

Patent Number: 5830701

This patent provides devices that can quantify hematopoietic stem cell numbers from a pool of cells through non-immunological means.

Inventors: Houwen, Berend (Redlands, CA); Tsujino, Yukio (Hyogo-ken, JP); Morikawa, Takashi (Hyogo-ken, JP); Ikeuchi, Yoshiro (Hyogo-ken, JP); Hamaguchi, Yukio (Hyogo-ken, JP)
Assignee: Tao Medical Electronics Co., Ltd. (JP)
Date of First Priority Issue: Friday March 28th, 1997

Method of detecting hematopoietic progenitor cells

Patent Number: RE39,006

This patent appears to cover a new method of detecting hematopoietic stem cells, without needing to use stem cell-specific markers. The patent seems to use some light and physical properties of the cells to distinguish between stem cells and non-stem cells. The patent has one issued claim which is: "A method for detecting or counting or both detecting and counting hematopoietic...

Inventors: Houwen, Berend (Redlands, CA); Tsujino, Yukio (Hyogo-ken, JP); Morikawa, Takashi (Hyogo-ken, JP); Ikeuchi, Yoshiro (Hyogo-ken, JP); Hamaguchi, Yukio (Hyogo-ken, JP); Wang, Fu-sheng (Hyogo, JP); Hirai, Kojiro (Hyogo, JP)
Assignee: Sysmex Corporation (Kobe, JP)
Date of First Priority Issue: Saturday March 1st, 1997

Composition and method for preserving progenitor cells

Patent Number: 7,112,653

This patent covers peptides that inhibit hematopoietic stem cell proliferation, thereby allowing protection of these cells from chemotherapy or radiotherapy. This patent may conceptually be applicable to selectively inhibiting healthy stem cells while allowing leukemic stem cells to proliferate so that chemotherapy or radiotherapy may selectively kill the proliferating leukemic cells.

Inventors: Moore; Jeffrey G. (Kennebunkport, ME)
Assignee: Inclone Systems, Incorporated (New York, NY)
Date of First Priority Issue: Monday December 9th, 1996

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