Delivery device for biological composites and method of preparation thereof

Patent Number: 6736799

This patent covers a device for administration of biological matrices that can be co-implanted with stem cells for regenerative purposes.

Inventors: Erbe, Erik M. (Berwyn, PA); Marx, Jeffrey G. (Downington, PA); Bagga, Charanpreet S. (Phoenixville, PA)

Assignee: Vita Licensing, Inc. (Wilmington, DE)

Date of First Priority Issue: Tuesday October 24th, 2000

Cardiac function comprising implantation of embryonic stem cell in which differentiation has been initiated

Patent Number: 6534052

This patent teaches how to administer embryonic stem cells, and differentiated cells thereof, into the area of infarcted myocardium so as to prevent future heart failure.

Inventors: Xiao, Yong-Fu (Wayland, MA); Morgan, James P. (Newton Centre, MA)

Assignee: None stated

Date of First Priority Issue: Tuesday September 5th, 2000

Plasma-derived fibrin-based matrices and tissue

Patent Number: 6787357

This patent provides matrices that can be generated easily in GMP conditions, and can be administered in combination with various stem cells for therapeutic benefits. Cytokines and other growth factors may also be administered with the stem cells into the matrix to either induce local proliferation, or to chemoattract endogenous stem cells.

Inventors: Bowlin, Gary L. (Mechanicsville, VA); Wnek, Gary (Midlothian, VA); Simpson, David G. (Mechanicsville, VA); Lam, Philippe (Richmond, VA); Carr, Marcus E. (Midlothian, VA); Fillmore, Helen (Richmond, VA)

Assignee: Virginia Commonwealth University (Richmond, VA)

Date of First Priority Issue: Friday September 1st, 2000

Composition for delivery of hematopoietic growth factor

Patent Number: 6875441

This patent teaches ways of formulating G-CSF so as to have better pharmacological properties. Specifically the patent is trying to address the problem of: "...administration of hematopoietic growth factors such as G-CSF, GM-CSF, SCF and Flt3-L, requires multiple daily injections. This, in turn leads to another common disadvantage of current injectable therapies...

Inventors: Rosenthal, Gary J. (Louisville, CO); Etter, Jeffrey B. (Boulder, CO)

Assignee: RxKinetix, Inc. (Louisville, CO)

Date of First Priority Issue: Friday May 26th, 2000

Combination growth factor therapy and cell therapy for treatment of acute and chronic heart disease
Patent Number: 7,166,280

Heart failure has been one of the main areas of stem cell research. Specifically, stem cells have previously been used clinically both for treatment of immediate post myocardial infarction (primarily to inhibit scar tissue and subsequent remodelling), as well as in patients with cardiac degeneration in absense of a myocardial infarct. The current patent is very interesting since it claims...
Inventors: Franco; Wayne P. (Rocky Hill, CT)

Assignee: None stated

Date of First Priority Issue: Thursday April 6th, 2000

Delivery of therapeutic biologicals from implantable tissue matrices
Patent Number: 6692738

This patent covers compositions of matter that can be used to deliver proteins to tissue. The matrices described in this patent can be seeded with cells for delivery of stem cells together with the therapeutic protein. In some embodiements of the patent the therapeutic protein can be an antibody, a growth factor, or a cytokine.

Inventors: MacLaughlin, David T. (Saugus, MA); Vacanti, Joseph P. (Winchester, MA); Donahoe, Patricia K. (Boston, MA); Masiakos, Peter T. (Boston, MA)

Assignee: The General Hospital Corporation (Boston, MA)

Date of First Priority Issue: Thursday January 27th, 2000

Cell delivery catheter and method
Patent Number: 6599274

This patent provides a medical device that can be utilized for administration of stem cells to localized areas of need using a catheter-based system.

Inventors: Kucharczyk, John (Bishop, GA); Gillies, George T., N/A (Charlottesville, VA); Broaddus, William C., Fillmore, Helen L.

Assignee: None Stated

Date of First Priority Issue: Saturday January 1st, 2000

Injectable hyaluronic acid derivative with pharmaceuticals/cells
Patent Number: 6699471

This patent teaches various forms of hyaloronic acid that may be administered in combination with stem cells for localization and better function of the stem cell. This patent is interesting in light of US patent application # 20060069064 which teaches "Methods for facilitating recovery of functions of endogenous or implanted or transplanted stem cells using hyaluronic acid"

Inventors: Radice, Marco (Modena, IT); Pastorello, Andrea (Abano Terme, IT); Pavesio, Alessandra (Padua, IT); Callegaro, Lanfranco (Thiene, IT)

Assignee: Fidia Advanced Biopolymers, SRL (Abano Terme, IT)

Date of First Priority Issue: Tuesday December 21st, 1999

Method and device for myogenesis and angiogenesis of the heart
Patent Number: 6551338

This patent covers ways of entering the myocardium through transthoracic means in order to administer angiogenic stimuli, which may include stem cells, or activators of stem cells that are associated with angiogenesis. The patent also discloses various administration devices.

Inventors: Chiu, Ray Chu-Jeng (Montreal, CA); Lachapelle, Kevin (Westmount, CA)

Assignee: McGill University (Montreal, CA)

Date of First Priority Issue: Wednesday September 1st, 1999

Foam composite for the repair or regeneration of tissue
Patent Number: 6306424

This patent provides various compositions of matter for making foam implants that can be used to deliver cells into a host.

Inventors: Vyakarnam, Murty N. (New York, NY); Zimmerman, Mark C. (East Brunswick, NJ); Scopelianos, Angelo George (Whitehouse Station, NJ); Chun, Iksoo (Flemington, NJ); Melican, Mora C. (Bridgewater, NJ); Bazilio, Clairene A. (Plainfield, NJ); Roller, Mark B. (Nor

Assignee: Ethicon, Inc. (Somerville, NJ)

Date of First Priority Issue: Wednesday June 30th, 1999

Order by:

<< | < | 1 2 3 4 5 6 7 | > | >>

TOP

Send us your feedback?