This patent relates to ways of delivering drugs (for example stem cell stimulating agents) to specific anatomical areas using an implantable, biodegradible approach. Specifically, the patent has 4 independent claims, the first 3 cover a delivery composition, and the 4th covers a scaffold.
This patent is useful for the induction of collateral blood vessel formation (for example angiogenesis) in ischemic tissue. There are numerous conditions that may benefit from induction of said collateral blood vessel formation. For example ischemia of the various organs may be treated using this patent. The patent overall teaches the use of autologous bone marrow cells, either ex vivo...
This patent teaches a method of administering cells, including stem cells, through use of a filament-type object. The object has a solid core and an outside sheath that is porous and to which cells can be attached to before administration. The invention teaches that hair follicle cells, cells that have been encapsulated, and cells that have been genetically engineered can be...
This patent teaches new compositions of matter based on hyaluronic acid that are useful for the administration of stem cells.
The problem with various grafts and prosthesis is that the body starts reacting to them, either through restenosis, or complement activation, or thrombosis. This patent teaches unique ways to generate grafts and prosthetics through the implantation of stem cells and/or other cellular components in the structure to be introduced into the body.
This patent provides methods and devices for administration of cells, including stem cells, via various prosthetic devices.
This patent covers the use of cells, including stem cells and derivatives, for producing certain drugs or proteins specifically upon stimulation. Stimulation may be electrical, mechanical, or chemical.
This teaches novel ways of encapsulating cells so that the immune system of the host does not reject them.
This patent teaches the generation of cells with implantable biodegradable material through culture in vitro with materials of various compositions. The patent may be used for generation of artificial tissue, or for creating clusters of cells that may be implantable for treatment of disease. The patent is particularly aimed at inducing generation of chondrocytes ex vivo or in vitro for...
This patent provides compositions of matter for administration of cells and cytokines into a host. The compositions are various polymers that are biodegradable, but can serve as delivery systems.