Patents (1325 Stem Cell Patents)

Class: Administration (70)

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Drug releasing biodegradable fiber for delivery of therapeutics

Patent Number: 7033603

This patent relates to ways of delivering drugs (for example stem cell stimulating agents) to specific anatomical areas using an implantable, biodegradible approach. Specifically, the patent has 4 independent claims, the first 3 cover a delivery composition, and the 4th covers a scaffold.

Inventors: Nelson, Kevin D. (Arlington, TX); Crow, Brent B. (Fort Worth, TX)
Assignee: Board of Regents The University of Texas (Austin, TX)
Date of First Priority Issue: Tuesday June 8th, 1999

Intramyocardial injection of autologous bone marrow

Patent Number: 7097832

This patent is useful for the induction of collateral blood vessel formation (for example angiogenesis) in ischemic tissue. There are numerous conditions that may benefit from induction of said collateral blood vessel formation. For example ischemia of the various organs may be treated using this patent. The patent overall teaches the use of autologous bone marrow cells, either ex vivo...

Inventors: Kornowski, Ran (Ramat hasharon, IL); Fuchs, Shmuel (Rockville, MD); Epstein, Stephen E. (Rockville, MD); Leon, Martin B. (New York, NY)
Assignee: Myocardial Therapeutics, Inc. (San Diego, CA)
Date of First Priority Issue: Tuesday March 30th, 1999

Filamentary means for introducing agents into tissue of a living host

Patent Number: 6884427

This patent teaches a method of administering cells, including stem cells, through use of a filament-type object. The object has a solid core and an outside sheath that is porous and to which cells can be attached to before administration. The invention teaches that hair follicle cells, cells that have been encapsulated, and cells that have been genetically engineered can be...

Inventor: Barrows, Thomas H. (Austell, GA)
Assignee: Aderans Research Institute, Inc. (Beverly Hills, CA)
Date of First Priority Issue: Monday February 8th, 1999

Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same

Patent Number: 6630457

This patent teaches new compositions of matter based on hyaluronic acid that are useful for the administration of stem cells.

Inventors: Aeschlimann, Daniel (Madison, WI); Bulpitt, Paul (Madison, WI)
Assignee: Orthogene LLC (Sausalito, CA)
Date of First Priority Issue: Friday September 18th, 1998

Methods for implanting cells

Patent Number: 6579313

The problem with various grafts and prosthesis is that the body starts reacting to them, either through restenosis, or complement activation, or thrombosis. This patent teaches unique ways to generate grafts and prosthetics through the implantation of stem cells and/or other cellular components in the structure to be introduced into the body.

Inventors: Dzau, Victor J. (Newton, MA); Pratt, Richard E. (Newton, MA); Mann, Michael J. (Newton, MA); Ehsan, Afshin (Boston, MA); Griese, Daniel P. (Boston, MA)
Assignee: The Bringham and Women's Hospital (Boston, MA)
Date of First Priority Issue: Friday July 10th, 1998

Methods for implanting cells

Patent Number: 6352555

This patent provides methods and devices for administration of cells, including stem cells, via various prosthetic devices.

Inventors: Dzau, Victor J. (Newton, MA); Pratt, Richard E. (Newton, MA); Mann, Michael J. (Newton, MA); Ehsan, Afshin (Boston, MA); Griese, Daniel P. (Boston, MA)
Assignee: The Brigham and Womens Hospital, Inc. (Boston, MA)
Date of First Priority Issue: Friday July 10th, 1998

Implantable system with drug-eluting cells for on-demand local drug delivery

Patent Number: 6206914

This patent covers the use of cells, including stem cells and derivatives, for producing certain drugs or proteins specifically upon stimulation. Stimulation may be electrical, mechanical, or chemical.

Inventors: Soykan, Orhan (New Brighton, MN); Donovan, Maura G. (St. Paul, MN) )
Assignee: Medtronic, Inc. (Minneapolis, MN
Date of First Priority Issue: Thursday April 30th, 1998

Cells or tissue attached to a non-degradable filamentous matrix encapsulated by a semi-permeable membrane

Patent Number: 6303136

This teaches novel ways of encapsulating cells so that the immune system of the host does not reject them.

Inventors: Li, Rebecca (Needham, MA); Rein, David (Providence, RI)
Assignee: Neurotech S.A. (Evry, FR)
Date of First Priority Issue: Monday April 13th, 1998

Method for fabricating cell-containing implants

Patent Number: 6886568

This patent teaches the generation of cells with implantable biodegradable material through culture in vitro with materials of various compositions. The patent may be used for generation of artificial tissue, or for creating clusters of cells that may be implantable for treatment of disease. The patent is particularly aimed at inducing generation of chondrocytes ex vivo or in vitro for...

Inventors: Frondoza, Carmelita G. (Woodstock, MD); Fink, David J. (Baltimore, MD); Hungerford, David S. (Cockeysville, MD); Shikani, Alan H. (Ruxton, MD)
Assignee: The Johns Hopkins University (Baltimore, MD) Chrondros, Inc. (Baltimore, MD)
Date of First Priority Issue: Thursday April 9th, 1998

Polymer constructs

Patent Number: 6514522

This patent provides compositions of matter for administration of cells and cytokines into a host. The compositions are various polymers that are biodegradable, but can serve as delivery systems.

Inventor: Domb, Abraham J. (Efrat, IL)
Assignee: Chondros, Inc. (Towson, MD)
Date of First Priority Issue: Wednesday April 8th, 1998

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