Class: Administration (70)
Molecules that home to various selected organs or tissues
Patent Number: 6933281This patent teaches the use of peptides that have the ability to home to specific tissues. Such homing peptides may be used to deliver drugs or therapeutic agents, as well as (conceptually) to administer activators of stem cells. The patent has 4 independent claims: - A lymph node homing peptide which is PTCAYGWCA (SEQ ID NO: 336). - A conjugate...
Bioabsorbable breast implant
Patent Number: 6881226This patent covers a breast implant that eventually resorbs and is replaced by endogenous tissue. The patent has claims covering not only the use for cosmetic reasons, but also for administration of therapeutic agents.
Devices for cloaking transplanted cells
Patent Number: 6368612This patent covers a device that can be implanted so as to protect the cells inside the device from immune mediated rejection. This is particularly useful for stem cell therapy and therapy with cells that are differentiated from stem cells because it would allow for the use of one cell source in all people. The device is also useful for transplantation of islet cells that are xenogeneic...
Membrane for in guided tissue regeneration
Patent Number: 6752834Disclosed is a matrix that is useful for administration of living stem cells particularly for treatment of bone or cartilage injuries. The matrix is comprised primarily of collagen II and is compatible with a variety of stem cell technologies. This patent is useful for numerous applications.
Method and system for myocardial infarction repair
Patent Number: 7031775This patent covers and implantable system made of cells, genes, other agents, together wtih a device that elecronically stimulates the cells. Specifically, the patent has 1 independent claim which covers a method of repairing the patient's myocardium through administration of a "cell repopulating source" and an "electrical stimulation device".
Stimulation, culture and preservation of pancreatic cells
Patent Number: 6479283This patent covers a method of administering beta cells in a matrix that allows for enhanced viability, as well as insulin production.
System for the in vivo delivery and expression of heterologous genes in the bone marrow
Patent Number: 6008035This patent covers a method of generating viruses that are useful for transfection in living beings. Specifically the viral approaches can be used to target bone marrow stem cells.
System for the in vivo delivery and expression of heterologous genes in the bone marrow
Patent Number: 5811407This patent teaches the transfection of bone marrow stem cells using a new type of vector. The vector disclosed is an alphavirus vector. Transfection by alphavirus has been performed in numerous situations and is actually in clinical trials.
Regeneration and augmentation of bone using mesenchymal stem cells
Patent Number: 6541024This patent teaches ways of generating bone tissue using mesenchymal stem cells that are placed into a special matrix. In one embodiment, the matrix and the mesenchymal stem cells are administered into an area of bone injury.
Systems and methods of use for delivering beneficial agents for revascularizing stenotic bypass grafts and other occluded blood vessels and for other purposes
Patent Number: 6569147This patent teaches methods of administering cells and fluids in order to prevent inflammation and induce regeneration in areas of stent placement.