Class: Administration (70)
Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
Patent Number: 6960351One of the main drawbacks of stem cell therapy, or any cell therapy for that matter is that it is important to avoid the issue of immunological rejection. This is why numerous scientists are using autologous stem cells. Unfortunately, there is no such thing as autologous embryonic stem cells. Additionally, the ability to use allogeneic stem cells without rejection would allow for the...
Implantable biocompatible immunoisolatory vehicle for the delivery of selected therapeutic products
Patent Number: 6322804This patent provides methods of encapsulating cells so that they will not be rejected by the recipient immune system. Encapsulation devices such as this should be considered not only for the protection of the cells that are administered, but also for protection of the host from the cells. For example, lets say that embryonic stem cells are administered into a degenerating organ for the...
Implantable biocompatable immunoisolatory vehicle for delivery of selected therapeutic products
Patent Number: 6083523This patent covers a device that is implantable, and explantable, that can be used for administration of stem cells so that they will not be rejected by the host immune system. It will be interesting to use such devices with embryonic stem cells so as to allow the embryonic stem cells to secrete soluble factors in vivo that hopefully will possess rejuvenating ability.
Methods for making immunoisolatory implantable vehicles with a biocompatiable jacket and a biocompatible matrix core
Patent Number: 5834001This patent teaches ways of generating devices that contain cells or stem cells that can be implanted without fear of immune mediated rejection.
Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
Patent Number: 5800829This patent provides a method of isolating cells from the immune system through encapsulation. Specific means of generating this implantable device, and use with stem cells, as well as other populations of cells is disclosed.
Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
Patent Number: 5800828This patent teaches ways of growing cells in vivo in an environment that is protected from immunological attack. Specific ways of encapsulating cells, including stem cells, and their progeny are described. This patent is useful, in one embodiment, for the treatment of diabetes with artificially generated islets.
Therapeutic delivery compositions and methods of use thereof
Patent Number: 6933286The introduction of nucleic acids into cells is a difficult task that has significantly hampered gene therapy. This patent discloses a novel method of getting nucleic acids into cells. The patent has 2 independent claims. The first covers a composition of nucleic acid sequences or one or more triplex DNA compounds, and a nonionic block copolymer. The second...
Intrapulmonary delivery of hematopoietic drug
Patent Number: 6012450This patent teaches the administration of hematopoietic stem cell stimulatory factors through the intrapulmonary route. This patent is interesting in light of the fact that exogenous stem cells generally go to the liver or lung.
System and method for transplantation of cells
Patent Number: 5423778This patent teaches the expansion of stem cells and progeny of the stem cells in vivo in a patient. The patent discloses various chambers, as well as methods of introducing the cells into a patient so that the cells can be truly cultured "in vivo".
Method of administering human pluripotent hematopoietic colony stimulating factor
Patent Number: 5662895This patent covers the hematopoietic uses of a tumor derived hematopoiesis stimulator called pluripotent colony stimulating factor...what is the modern name of this???