Class: Mobilization (25)
Method of mobilizing hematopoietic stem cells
Patent Number: 6447766Inventors: Pelus, Louis Martin (Richboro, PA); King, Andrew Garrison (Blue Bell, PA); Qian, Yanqiu (King of Prussia, PA)
Assignee: SmithKline Beecham Corporation (Philadelphia, PA)
Date of First Priority Issue: Tuesday June 8th, 1993
Peripheralization of hematopoietic stem cells
Patent Number: 5843438This patent covers the use of anti-VLA-4 and anti-VCAM antibodies for mobilizing stem cells from the bone marrow. Stem cell mobilization is induced by the antibodies blocking the binding of the hematopoietic stem cells to the bone marrow stroma.
Inventor: Papayannopoulou, Thalia (Seattle, WA)
Assignee: Board of Regents University of Washington (Seattle, WA)
Date of First Priority Issue: Friday November 13th, 1992
Peripheralization of hematopoietic stem cells
Patent Number: 5824304This patent teaches how to treat HIV by removal of mobilized stem cells (stem cell mobilization by anti-VLA4 antibody), administering chemo or radiotherapy, and then subsequently reinfusing the purified stem cells to reconstitute the hematopoietic system.
Inventor: Papayannopoulou, Thalia (Seattle, WA)
Assignee: None Stated
Date of First Priority Issue: Friday November 13th, 1992
Peripheralization of hematopoietic stem cells
Patent Number: 5695755This patent covers mobilization of hematopoietic stem cells by administration of antibodies to VCAM or VLA-4.
Inventor: Papayannopoulou, Thalia (Seattle, WA)
Assignee: None stated
Date of First Priority Issue: Friday November 13th, 1992
Method for homing hematopoietic stem cells to bone marrow stromal cells
Patent Number: 6258354This patent covers the use of gene transfected stromal cells in order to increase engraftment of a hematopoietic stem cell transplant.
Inventor: Greenberger, Joel S. (Lincoln, MA
Assignee: none stated
Date of First Priority Issue: Friday September 29th, 1989