Class: Type (179)
Primitive cell colony stimulating factors and lymphohematopoietic progenitor cells
Patent Number: 5256560There are numerous stem cell types in the bone marrow. Specific stem cells of the hematopoietic lineage were originally identified as being CD34+. In this patent, a CD34-stem cell is claimed that produces growth factors capable of stimulating hematopoiesis. This patent may be a really great candidate for developing since at first...
Homogeneous mammalian hematopoietic stem cell composition
Patent Number: 5087570This patent covers the use of the stem cell antigen (SCA-1) for determination of murine hematopoieitic stem cells. The patent has 1 independent claim that covers "A cell composition consisting essentially of as the cellular population viable murine hematopoietic Sca-1+ stem cells from a genetically identical or congenic source."
Yolk sac stem cells and their uses
Patent Number: 5744347This patent covers an early hematopoietic stem cell that is derived from the yolk sac. The yolk sac is actually the first site, or one of the first sites of hematopoiesis during development.
Human stem cells and monoclonal antibodies
Patent Number: 5035994This patent futher strengthens Civin's claim (no pun intended) on the hematopoietic stem cell. The first independent claim covers "A method of isolating a population of human cells containing pluripotent lympho-hematopoletic stem cells" through ANY ANTIBODY that bind to the antigen that is recognized by the antibody deposited with ATCC... This patent covers a type of bone marrow immune suppressive cell that appears to be related to what is currently called the NKT cell. This suppressor cell may also be related to the classical "natural suppressor cell" which is a myeloid progenitor with immune suppressive properties.
The cells in this patent are useful for the treatment of autoimmunity and... This patent is similar to 5035994 and 4965204 by Civin. Essentially the current patent has 3 independent claims that cover similar subject matter as the other two mentioned patents. Specifically, "A method of transplanting stem cells comprising: (a) providing a suspension of human cells comprising pluripotent lympho-hematopoietic stem cells substantially free of mature lymphoid and... This is one of the most important patents in the history of stem cell IP. It essentially covers the hematopoietic CD34+ stem cell. The patent has 3 independent claims, the first covering a population of hematopoietic cells in general, the second covering hematopoietic cells from blood, and the third covering hematopoietic cells which are... Cancer stem cells have been known to exist for decades, as seen by the present patent whose actual first priority date is july 7, 1978.
Unfortunately, research into cancer stem cells is only recently gaining attention.
The cancer stem cell is the populatin which some believe is responsible for maintaining the tumor mass, while the other 99% of cancer cells are differentiated and have... This patent covers the use of osteoblasts to stimulate activity and function of hematopoietic stem cells. I wonder if osteoblasts can also stimulate the activity of other types of stem cells?
Suppressor and progenitor cells
Patent Number: 5985656
Human stem cells and monoclonal antibodies
Patent Number: 5130144
Human stem cells
Patent Number: 4714680
Primary bioassay of human tumor stem cells
Patent Number: 4411990
Hematopoietic cells: compositions and methods
Patent Number: 5733541