Human stem cells

Patent Number: 4714680

This is one of the most important patents in the history of stem cell IP. It essentially covers the hematopoietic CD34+ stem cell. The patent has 3 independent claims, the first covering a population of hematopoietic cells in general, the second covering hematopoietic cells from blood, and the third covering hematopoietic cells which are...

Inventor: Civin, Curt I. (Baltimore, MD)

Assignee: The Johns Hopkins University (Baltimore, MD)

Date of First Priority Issue: Saturday June 2nd, 1984

Primary bioassay of human tumor stem cells

Patent Number: 4411990

Cancer stem cells have been known to exist for decades, as seen by the present patent whose actual first priority date is july 7, 1978. Unfortunately, research into cancer stem cells is only recently gaining attention. The cancer stem cell is the populatin which some believe is responsible for maintaining the tumor mass, while the other 99% of cancer cells are differentiated and have...

Inventors: Salmon, Sydney E. (Tucson, AZ); Hamburger, Anne W. (Potomac, MD)

Assignee: University Patents, Inc. (Norwalk, CT)

Date of First Priority Issue: Tuesday January 1st, 1980

Hematopoietic cells: compositions and methods

Patent Number: 5733541

This patent covers the use of osteoblasts to stimulate activity and function of hematopoietic stem cells. I wonder if osteoblasts can also stimulate the activity of other types of stem cells?

Inventors: Taichman, Russell S. (Ann Arbor, MI); Emerson, Stephen G. (Wayne, PA)

Assignee: The Regent of the University of Michigan (Ann Arbor, MI)

Date of First Priority Issue: Tuesday November 30th, 1999

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