Class: Type (179)
Immortalized bone marrow mesenchymal stem cell
Patent Number: 6645763This patent has one claim that covers a specific mesenchymal stem cell population that is immortalized and appears to contain a gene associated with immortalization.
Composite blastocysts (CBs) from aggregates of dissociated cells of non-viable pre-embryos
Patent Number: 6759244This patent teaches methods of generating a composite blastocyst from non-viable embryos. The invention is useful for generation of stem cells of embryonic origin through a novel method.
Stem cells that transform to beating cardiomyocytes
Patent Number: 7,220,582Telomerase immortalized neural progenitor cells
Patent Number: 7,150,989Telemerase is critical for maintain telomere length and preventing senescence once cells have reached the Hayflick limit. This patent teaches the use of transfection with telomerase reverse transcriptase in order to generate neural progenitors that are immortal. The patent covers a wide variety of neural progenitors and sources of neural progenitors, including, dopaminergic, cholinergic...
Human ovarian mesothelial cells and methods of isolation and uses thereof
Patent Number: 6893871This is a patent covering an ovarian stem cell that can become either overian epithelial tissue, as well as granulosa tissue. The three independent claims are: A method of providing a source of immunogen to a heterologous recipient, comprising administering a plurality of ovarian mesothelial cells in an amount effective to induce an immune response in said recipient...
Early stage multipotential stem cells in colonies of bone marrow stromal cells
Patent Number: 7056738This is a composition of matter patent on a type of bone marrow derived stem cell. The authors state that marrow stromal cells (MSCS) are adult stem cells from bone marrow that can differentiate into multiple non-hematopoietic cell lineages. The authors identified that colonies of human MSCs contain both small, rapidly self-renewing stem cells (RS cells) and large...
Telomerizing nuclear donor cells and improving the efficiency on nuclear transfer
Patent Number: 7,265,262This patent covers methods of generating transgenic animals through the use of donor cells that express the telomerase reverse transcriptase. The expression of telomerase in the donor cell apparently increases the efficacy of cloning. There are 4 independent claims in the patent, all covering "a method for generating transgenic non-primate mammals by nuclear transfer", and all containing...
Human mesenchymal progenitor cell
Patent Number: 6936281This is a composition of matter patent for mesenchymal stem cell progenitors. The first three independent claims of this patent are restricted to generation of these cells from a Dexter type culture system (a specific type of long term culture in which adherent cells are allowed to form a layer and the hematopoietic cells rely on their support). The forth independent claim is not restricted...
Pigment epithelial cell of the eye, its production and use in therapy of an eye or CNS disease
Patent Number: 7,247,479This patent covers a method for producing a pigment epithelial cell of the eye through in vivo transfection of therapeutic genes such as neurotrophic factors, antiangiogenic factors, antioxidative factors, lysosomal factors, and/or vasodilating factors.
Renal stem cells and uses thereof
Patent Number: 6458588This patent covers a renal stem cell that is identified based on expression of the markers flk-1 and Sca-1. It is interesting how some many stem cells of different tissues all express similar markers and in some situations similar properties. Examples of such similarities include expression of Sca-1 (which appropriately stands for "stem cell antigen") on stem cells ranging from...