This patent covers a type of bone marrow immune suppressive cell that appears to be related to what is currently called the NKT cell. This suppressor cell may also be related to the classical "natural suppressor cell" which is a myeloid progenitor with immune suppressive properties. The cells in this patent are useful for the treatment of autoimmunity and...
This patent is similar to 5035994 and 4965204 by Civin. Essentially the current patent has 3 independent claims that cover similar subject matter as the other two mentioned patents. Specifically, "A method of transplanting stem cells comprising: (a) providing a suspension of human cells comprising pluripotent lympho-hematopoietic stem cells substantially free of mature lymphoid and...
This is one of the most important patents in the history of stem cell IP. It essentially covers the hematopoietic CD34+ stem cell. The patent has 3 independent claims, the first covering a population of hematopoietic cells in general, the second covering hematopoietic cells from blood, and the third covering hematopoietic cells which are...
Cancer stem cells have been known to exist for decades, as seen by the present patent whose actual first priority date is july 7, 1978. Unfortunately, research into cancer stem cells is only recently gaining attention. The cancer stem cell is the populatin which some believe is responsible for maintaining the tumor mass, while the other 99% of cancer cells are differentiated and have...
This patent covers the use of osteoblasts to stimulate activity and function of hematopoietic stem cells. I wonder if osteoblasts can also stimulate the activity of other types of stem cells?