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Patents (1374 Stem Cell Patents)

Class: Type (183)

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Engraftable human neural stem cells

Patent Number: 6680198

This patent teaches a type of neuronal stem cell that can be used for cell therapy of neurological disorders. Characterization of the cell is provided and includes expression of EGF and FGF receptors.

Inventors: Snyder, Evan Y. (Jamaica Plain, MA); Wolfe, John H. (Philadelphia, PA); Kim, Seung U. (Vancouver, CA)
Assignee: The Children's Medical Center Corporation (Boston, MA) University of British Columbia (Vancouver, GB) University of Pennsylvania (Philadelphia, PA)
Date of First Priority Issue: Friday August 14th, 1998

Engraftable human neural stem cells

Patent Number: 6541255

These are stem cells that are isolated from human fetal telencephalon and are useful for engrafting and generating various neuronal structures.

Inventors: Snyder, Evan Y. (Jamaica Plain, MA); Wolfe, John H. (Philadelphia, PA); Kim, Seung U. (Vancouver, CA)
Assignee: The Children's Medical Center Corporation (Boston, MA) The University of British Columbia (CA) The University of Pennsylvania (Philadelphia, PA)
Date of First Priority Issue: Friday August 14th, 1998

Engraftable human neural stem cells

Patent Number: 5958767

This patent covers a type of neural stem cells that is isolated from human fetal telencephalon. This stem cell can be propagated in vitro and subsequently implanted for therapeutic benefit in a wide variety of animal models.

Inventors: Snyder, Evan Y. (Jamaica Plain, MA); Wolfe, John H. (Philadelphia, PA); Kim, Seung U. (Vancouver, CA)
Assignee: The Children's Medical Center Corp. (Boston, MA)
Date of First Priority Issue: Friday August 14th, 1998

Genetically modified CD34-negative adherently growing stem cells and their use in gene therapy

Patent Number: 6361997

This patent provides stem cells that are mesenchymal-like or lack expression of CD34, for the purpose of transfection with a foreign gene.

Inventor: Huss, Ralf (83666 Waakirchen, DE)
Assignee: None Stated
Date of First Priority Issue: Friday July 24th, 1998

Liver stem cell

Patent Number: 6872389

This patent covers a liver stem cell that is isolated based on expression of the marker OV6. These cells could be used for a variety of therapeutic purposes including hepatitis. Liver cell therapy can be performed by administration of single cell suspensions, additionally attractive with this patent is that liver cells are generally more tolerogenic and less likely...

Inventor: Faris, Ronald A. (Providence, RI)
Assignee: Rhode Island Hospital (Providence, RI)
Date of First Priority Issue: Friday July 10th, 1998

Liver stem cell

Patent Number: 6129911

This patent covers the stem cell for livers. Given the strong regenerative capacity of the liver, the characterization of stem cells of this organ is of great interest. Specific markers and methods of expanding liver stem cells are provided. The patent is currently owned by a company called MultiCell.

Inventor: Faris, Ronald A. (Providence, RI)
Assignee: Rhode Island Hospital, A LifeSpan Partner (Providence, RI)
Date of First Priority Issue: Friday July 10th, 1998

Compositions and methods for use in affecting hematopoietic stem cell populations in mammals

Patent Number: 6586192

This patent seems to cover a type of hematopoietic stem cell that is positive for expression of the marker KDR-1.

Inventors: Peschle, Cesare (Rome, IT); Ziegler, Benedikt L. (Tuebingen, DE)
Assignee: Thomas Jefferson University (Philadelphia, PA) Instituto Superiore di Sanita (Rome, IT)
Date of First Priority Issue: Friday May 29th, 1998

Human mesenchymal stem cells

Patent Number: 6387367

This patent covers mesenchymal stem cells and provides a specific phenotype for them which includes CD45+, SH2,3,4+, and in some cases CD14+. This patent is important for anyone operating in the area of mesenchymal stem cells since it essentially covers the use of this specific cell population. Patents on...

Inventors: Davis-Sproul, Janice M. (Towson, MD); Moorman, Mark Aaron (Baltimore, MD); McNeil, Renee Marie (Baltimore, MD); Simonetti, Jr., Donald William (Forest Hill, MD); Hammill, Lora Catherine (Bel Air, MD); Craig, Stewart (Timonium, MD)
Assignee: Osiris Therapeutics, Inc. (Baltimore, MD)
Date of First Priority Issue: Friday May 29th, 1998

Method of isolating ependymal neural stem cells

Patent Number: 6541247

This patent covers stem cells of the ependymal CNS type from an animal that is non-embryonic. These neuronal stem cells can be isolated based on expression of Notch-1 receptor.

Inventors: Frisen, Jonas (Stockholm, SE); Janson, Ann Marie (Stockholm, SE); Johansson, Clas (Stockholm, SE); Momma, Stefan (Sp.ang.nga, SE); Clarke, Diana (Stockholm, SE); Zhao, Ming (Solna, SE); Lendahl, Urban (Sundbyberg, SE); Delfani, Kioumars (Solna, SE)
Assignee: Neuronova AB (Stockholm, SE)
Date of First Priority Issue: Monday May 25th, 1998

Bone marrow cells as a source of neurons for brain and spinal cord repair

Patent Number: 6528245

This patent teaches that bone marrow stromal cells may be used as a source of neurons or to assist in neuronal regeneration. One wonders if these bone marrow stromal cells are similar to the mesenchymal stem cells that are patented by Osiris Therapeutics.

Inventors: Sanchez-Ramos, Juan (Tampa, FL); Song, Shijie (Tampa, FL); Janssen, William (Tampa, FL); Sanberg, Paul (Spring Hill, FL); Freeman, Thomas (Tampa, FL)
Assignee: University of South Florida (Tampa, FL)
Date of First Priority Issue: Thursday May 7th, 1998
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