Patents (1325 Stem Cell Patents)

Class: 3D Culture/Scaffold (88)

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Instrument for regenerating living organism tissue or organ

Patent Number: 6953482

Essentially the invention is a scaffold with a tube-like feature in which cells may be grown outside of the body to form an organ or tissue, and then will be used for implantation into the host. The tube-like features of the scaffold allow for growth of neurons, blood vessels, trachea, and other bodily parts. The patent has 2 independent claims. The first covers general features of the...

Inventors: Doi, Nobutoshi (Osaka, JP); Matsuda, Kazuhisa (Osaka, JP); Hata, Ken-ichiro (Kariya, JP); Sakai, Kensuke (Aichi, JP)
Assignee: Nipro Corporation (Osaka, JP) Ueda, Minoru (Nisshin, JP)
Date of First Priority Issue: Thursday April 26th, 2001

Implantable artificial organ and physiological monitoring system

Patent Number: 6750055

This patent covers an implantable culture system that uses islet cells and/or stem cells for treatment of diabetes. What is interesting about this patent is that it actually involves a mechanism of detecting insulin so that the culture system and other additions to the body can be perform in order to maintain homeostatic insulin concentrations. This patent is useful for small biotechs...

Inventors: Connelly, Patrick R. (Rochester, NY); Weiner, Michael L. (Webster, NY)
Assignee: Biomed Solutions LLC (West Henrietta, NY)
Date of First Priority Issue: Wednesday March 7th, 2001

Injection molding of living tissues

Patent Number: 6773713

This patent teaches how to combine computer engineering design tools together with stem cell technologies for the formation of 3 dimensional tissues that may subsequently be implanted.

Inventors: Bonassar, Lawrence J. (Acton, MA); Rowley, Jon A. (Chapel Hill, NC); Mooney, David J. (Ann Arbor, MI)
Assignee: University of Massachusetts (Boston, MA)
Date of First Priority Issue: Friday February 23rd, 2001

Tissue matrices comprising placental stem cells, and methods of making the same

Patent Number: 7,311,904

The use of decellularized tissue as a scaffold onto which stem cells may be seeded has previously been patented. In the current patent the unique approach is taken that embryonic-like stem cells, as described in patent 7,311,905 are utilized to seed the...

Inventors: Hariri; Robert J. (Florham Park, NJ)
Assignee: Anthrogenesis Corporation (Summit, NJ)
Date of First Priority Issue: Wednesday February 14th, 2001

Methods of generating tissue using devitalized, acellular scaffold matrices derived from micro-organs

Patent Number: 7,297,540

In the area of stem cell biology many say that "microenvironment is everything". In the current patent, the inventors take this literally. They developed a method of taking tissue, decellularizing it, and using it as a scaffold for new stem cells to grow on. The invention covers such an approach for the generation of "mini-organs" or "micro-organs" including, small subsets of skin, lung...

Inventors: Mitrani; Eduardo N. (Jerusalem, IL)
Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem (Jerusalem, IL)
Date of First Priority Issue: Monday January 15th, 2001

Process for ex vivo formation of mammalian bone and uses thereof

Patent Number: 6811776

This patent teaches how to use bone stem cells, or bone precursor cells in order to generate in vitro bones that can be subsequently introduced in vivo. The invention is of use to any biotech interested in entering the regenerative market in the area of osteogenesis.

Inventors: Kale, Sujata (Boston, MA); Long, Michael W. (Northville, MI)
Assignee: The Regents of the University of Michigan (Ann Arbor, MI)
Date of First Priority Issue: Wednesday December 27th, 2000

Implantable biodegradable devices for musculoskeletal repair or regeneration

Patent Number: 7,192,604

The current patent covers methods of producing biodegradable scaffolds for implantation of stem cells, committed progenitors, or differentiated cells into a host primarily for the purposes of healing or regenerating musculoskeletal tissue. Covered is an implantable device made of fibers with varying degrees of biodegradability designed so that scaffold degradation is coordinated with...

Inventors: Brown; Kelly R. (Hillsborough, NJ), Chun; Iksoo (Flemington, NJ), Hammer; Joseph J. (Bridgewater, NJ), Janas; Victor F. (Monroe Township, NJ), Mandanas; Jennifer (Painted Post, NY), Melican; Mora C (Bridgewater, NJ), Rezania; Alireza (Hillsborough, NJ), Z
Assignee: Ethicon, Inc. (Somerville, NJ)
Date of First Priority Issue: Friday December 22nd, 2000

Vitro engineered, regenerated urinary tract tissue compositions and methods for producing same

Patent Number: 7,122,200

This patent covers ways of generating an artificial urinary tract through tissues engineering and culture of stem cells.

Inventors: Kropp; Bradley P. (Edmond, OK), Cheng; Earl Y. (Edmond, OK), Zhang; Yuan Yuan (Edmond, OK), Cowan; Rick (Oklahoma City, OK), Moore; Peter (Perry, OK)
Assignee: The Board of Regents of the University of Oklahoma (Norman, OK)
Date of First Priority Issue: Friday December 8th, 2000

Processing fetal or neo-natal tissue to produce a scaffold for tissue engineering

Patent Number: 6696074

This patent teaches how to make scaffolds that are useful for subsequent seeding with stem cells and generating tissues. The scaffolds seem to be made from decellularized tissues, including fetal and xenogeneic (in some cases) sources.

Inventors: Dai, Jianwu (Boston, MA); Bell, Eugene (Boston, MA); Russakovsky, Vladimir (Boston, MA)
Assignee: TEI Biosciences, Inc. (Boston, MA)
Date of First Priority Issue: Monday December 4th, 2000

Methods and compositions for culturing a biological tooth

Patent Number: 6899915

Inventors: Yelick, Pamela C. (Concord, MA); Bartlett, John D. (Acton, MA); Vacanti, Joseph P. (Winchester, MA); Olsen, Bjorn R. (Milton, MA); Stashenko, Phillip (Medfield, MA)
Assignee: President and Fellows of Harvard College (Cambridge, MA) General Hospital Corporation (Boston, MA) Forsyth Dental Infirmary for Children, Inc. (Boston, MA)
Date of First Priority Issue: Wednesday November 29th, 2000

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