Class: 3D Culture/Scaffold (88)
Patent Number: 6953482
Essentially the invention is a scaffold with a tube-like feature in which cells may be grown outside of the body to form an organ or tissue, and then will be used for implantation into the host. The tube-like features of the scaffold allow for growth of neurons, blood vessels, trachea, and other bodily parts. The patent has 2 independent claims. The first covers general features of the...
Inventors: Doi, Nobutoshi (Osaka, JP); Matsuda, Kazuhisa (Osaka, JP); Hata, Ken-ichiro (Kariya, JP); Sakai, Kensuke (Aichi, JP)
Assignee: Nipro Corporation (Osaka, JP)
Ueda, Minoru (Nisshin, JP)
Date of First Priority Issue: Thursday April 26th, 2001
Patent Number: 6750055
This patent covers an implantable culture system that uses islet cells and/or stem cells for treatment of diabetes. What is interesting about this patent is that it actually involves a mechanism of detecting insulin so that the culture system and other additions to the body can be perform in order to maintain homeostatic insulin concentrations.
This patent is useful for small biotechs...
Inventors: Connelly, Patrick R. (Rochester, NY); Weiner, Michael L. (Webster, NY)
Assignee: Biomed Solutions LLC (West Henrietta, NY)
Date of First Priority Issue: Wednesday March 7th, 2001
Patent Number: 6773713
This patent teaches how to combine computer engineering design tools together with stem cell technologies for the formation of 3 dimensional tissues that may subsequently be implanted.
Inventors: Bonassar, Lawrence J. (Acton, MA); Rowley, Jon A. (Chapel Hill, NC); Mooney, David J. (Ann Arbor, MI)
Assignee: University of Massachusetts (Boston, MA)
Date of First Priority Issue: Friday February 23rd, 2001
Patent Number: 7,311,904
The use of decellularized tissue as a scaffold onto which stem cells may be seeded has previously been patented.
In the current patent the unique approach is taken that embryonic-like stem cells, as described in patent 7,311,905 are utilized to seed the...
Inventors: Hariri; Robert J. (Florham Park, NJ)
Assignee: Anthrogenesis Corporation (Summit, NJ)
Date of First Priority Issue: Wednesday February 14th, 2001
Patent Number: 7,297,540
In the area of stem cell biology many say that "microenvironment is everything". In the current patent, the inventors take this literally. They developed a method of taking tissue, decellularizing it, and using it as a scaffold for new stem cells to grow on.
The invention covers such an approach for the generation of "mini-organs" or "micro-organs" including, small subsets of skin, lung...
Inventors: Mitrani; Eduardo N. (Jerusalem, IL)
Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem (Jerusalem, IL)
Date of First Priority Issue: Monday January 15th, 2001
Patent Number: 6811776
This patent teaches how to use bone stem cells, or bone precursor cells in order to generate in vitro bones that can be subsequently introduced in vivo. The invention is of use to any biotech interested in entering the regenerative market in the area of osteogenesis.
Inventors: Kale, Sujata (Boston, MA); Long, Michael W. (Northville, MI)
Assignee: The Regents of the University of Michigan (Ann Arbor, MI)
Date of First Priority Issue: Wednesday December 27th, 2000
Patent Number: 7,192,604
The current patent covers methods of producing biodegradable scaffolds for implantation of stem cells, committed progenitors, or differentiated cells into a host primarily for the purposes of healing or regenerating musculoskeletal tissue.
Covered is an implantable device made of fibers with varying degrees of biodegradability designed so that scaffold degradation is coordinated with...
Inventors: Brown; Kelly R. (Hillsborough, NJ), Chun; Iksoo (Flemington, NJ), Hammer; Joseph J. (Bridgewater, NJ), Janas; Victor F. (Monroe Township, NJ), Mandanas; Jennifer (Painted Post, NY), Melican; Mora C (Bridgewater, NJ), Rezania; Alireza (Hillsborough, NJ), Z
Assignee: Ethicon, Inc. (Somerville, NJ)
Date of First Priority Issue: Friday December 22nd, 2000
Patent Number: 7,122,200
This patent covers ways of generating an artificial urinary tract through tissues engineering and culture of stem cells.
Inventors: Kropp; Bradley P. (Edmond, OK), Cheng; Earl Y. (Edmond, OK), Zhang; Yuan Yuan (Edmond, OK), Cowan; Rick (Oklahoma City, OK), Moore; Peter (Perry, OK)
Assignee: The Board of Regents of the University of Oklahoma (Norman, OK)
Date of First Priority Issue: Friday December 8th, 2000
Patent Number: 6696074
This patent teaches how to make scaffolds that are useful for subsequent seeding with stem cells and generating tissues. The scaffolds seem to be made from decellularized tissues, including fetal and xenogeneic (in some cases) sources.
Inventors: Dai, Jianwu (Boston, MA); Bell, Eugene (Boston, MA); Russakovsky, Vladimir (Boston, MA)
Assignee: TEI Biosciences, Inc. (Boston, MA)
Date of First Priority Issue: Monday December 4th, 2000
Patent Number: 6899915
Inventors: Yelick, Pamela C. (Concord, MA); Bartlett, John D. (Acton, MA); Vacanti, Joseph P. (Winchester, MA); Olsen, Bjorn R. (Milton, MA); Stashenko, Phillip (Medfield, MA)
Assignee: President and Fellows of Harvard College (Cambridge, MA) General Hospital Corporation (Boston, MA) Forsyth Dental Infirmary for Children, Inc. (Boston, MA)
Date of First Priority Issue: Wednesday November 29th, 2000