Patents (1329 Stem Cell Patents)

Class: 3D Culture/Scaffold (88)

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Porous tissue scaffoldings for the repair or regeneration of tissue

Patent Number: 6365149

This patent covers the composition of matter and use of a specialized foam that can be embedded with stem cells and inserted in vivo, or can be inserted in vivo with chemoattractants for stem cells so that the endogenous stem cells repopulate it.

Inventors: Vyakarnam, Murty N. (Edison, NJ); Zimmerman, Mark C. (East Brunswick, NJ); Scopelianos, Angelo George (Whitehouse Station, NJ); Roller, Mark B. (North Brunswick, NJ); Gorky, David V. (Flemington, NJ)
Assignee: Ethicon, Inc. (Somerville, NJ)
Date of First Priority Issue: Wednesday June 30th, 1999

Porous tissue scaffoldings for the repair of regeneration of tissue

Patent Number: 6333029

This patent provides compositions of matter, and their uses, for generation of foams and various implantable structures that can function as scaffolds for the generation of artificial tissues.

Inventors: Vyakarnam, Murty N. (Edison, NJ); Zimmerman, Mark C. (East Brunswick, NJ); Scopelianos, Angelo George (Whitehouse Station, NJ); Roller, Mark B. (North Brunswick, NJ); Gorky, David V. (Flemington, NJ)
Assignee: Ethicon, Inc. (Somerville, NJ)
Date of First Priority Issue: Wednesday June 30th, 1999

Generation of viable cell active biomaterial patterns by laser transfer

Patent Number: 6905738

This patent was included the 3d culture/scaffold section since it doesnt really seem to fit anywhere else. Essentially the patent teachs how to write on cells (including stem cells) using laser light. The patent has 1 independent claim, which is: A method for laser deposition comprising the steps of; providing one or more sources of laser energy that produce laser...

Inventors: Ringeisen, Bradley R. (Alexandria, VA); Chrisey, Douglas B. (Bowie, MD); Pique, Alberto (Crofton, MD); McGill, R. Andrew (Lorton, VA)
Assignee: The United States of America as represented by the Secretary of the Navy (Washington, DC)
Date of First Priority Issue: Tuesday May 25th, 1999

Mineralization and biological modification of biomaterial surfaces

Patent Number: 6767928

This patent covers ways of altering biomaterials so that bone may be grown around them. Specifically useful is the application of such biomaterials as scaffolds around which stem cells can be grown in order to generate tissues that can be implanted.

Inventors: Murphy, William L. (Ann Arbor, MI); Peters, Martin C. (Ann Arbor, MI); Mooney, David J. (Ann Arbor, MI); Kohn, David H. (Ann Arbor, MI)
Assignee: The Regents of the University of Michigan (Ann Arbor, MI)
Date of First Priority Issue: Friday March 19th, 1999

Scaffold for tissue engineering cartilage having outer surface layers of copolymer and ceramic material

Patent Number: 6692761

This patent covers scaffolds that can be seeded with cells and/or growth factors so as to promote regeneration of cartilage.

Inventors: Mahmood, Tahir (Cambridge, MA); Riesle, Jens Uwe (Amsterdam, NL); van Blitterswijk, Clemens Antoni (Hekendorp, NL)
Assignee: IsoTis N.V. (Bilthoven, NL)
Date of First Priority Issue: Wednesday February 10th, 1999

Method for vocal cord reconstruction

Patent Number: 6918396

This invention is useful for repairing injuries to head and neck tissue through use of vertebrate-derived submucosa or basement membrane matrices as a graft for the regeneration and repair of said head and neck soft tissues. Specifically, it is known that a) The naturally-occurring extracellular matrix (ECM) of the small intestinal submucosa, as well as other vertebrate sources of...

Inventors: Badylak, Stephen F. (West Lafayette, IN); Spievack, Alan R. (Cambridge, MA)
Assignee: Purdue Research Foundation (West Lafayette, IN) Clarian Health Partners, Inc. (Indianapolis, IN)
Date of First Priority Issue: Tuesday December 1st, 1998

Lymphoid tissue-specific cell production from hematopoietic progenitor cells in three-dimensional devices

Patent Number: 7,192,769

The current invention teaches methods of generating 3-dimensional culture conditions for the expansion of lymphocytes out of hematopoietic stem cells. The invention specifically covers the production of T cells through the culture of a hematopoietic stem cell together with a lymphoid stromal element in the presence of an antigen presenting cell. Lymphoid stromal elements may be allogeneic...

Inventors: Pykett; Mark J. (Boxford, MA), Rosenzweig; Michael (Boston, MA), Scadden; David T. (Weston, MA), Poznansky; Mark C. (Charlestown, MA)
Assignee: Cytomatrix, LLC (Chelmsford, MA)
Date of First Priority Issue: Thursday November 12th, 1998

Cardiovascular components for transplantation and methods of making thereof

Patent Number: 6695879

This patent provides compositions of matter useful for the treatment of cardiac valve dysfunctions. The compositions may be seeded with stem cells, or may be implanted as scaffolds that naturally become cellularized.

Inventor: Bell, Eugene (Boston, MA)
Assignee: TEI Biosciences, Inc. (Boston, MA)
Date of First Priority Issue: Tuesday October 20th, 1998

Method and device for preparing a dental implant by immersion in a culture of mesenchymal cells

Patent Number: 6589525

This patent teaches how to use various cells, including stem cells, for generation of a dental implant.

Inventor: Gault, Philippe (Orleans, FR)
Assignee: Societe Anonyme Natural Implant (Brest, FR)
Date of First Priority Issue: Tuesday October 13th, 1998

Composites for tissue regeneration and methods of manufacture thereof

Patent Number: 6454811

This patent provides various engineering techniques and devices for generation of artificial tissue from biological sources in vitro and in vivo. Specific material and ways of manipulating the materials to design cellular substrates and shape inducing structures are disclosed.

Inventors: Sherwood, Jill K. (Princeton, NJ); Griffith, Linda G. (Cambridge, MA); Brown, Scott (Princeton, NJ)
Assignee: Massachusetts Institute of Technology (Cambridge, MA) Therics, Inc. (Princeton, NJ)
Date of First Priority Issue: Monday October 12th, 1998

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