Class: 3D Culture/Scaffold (89)
Patent Number: 6454811
This patent provides various engineering techniques and devices for generation of artificial tissue from biological sources in vitro and in vivo.
Specific material and ways of manipulating the materials to design cellular substrates and shape inducing structures are disclosed.
Inventors: Sherwood, Jill K. (Princeton, NJ); Griffith, Linda G. (Cambridge, MA); Brown, Scott (Princeton, NJ)
Assignee: Massachusetts Institute of Technology (Cambridge, MA) Therics, Inc. (Princeton, NJ)
Date of First Priority Issue: Monday October 12th, 1998
Patent Number: 6530956
This patent teaches how to make scaffolds that can be implanted in order to promote healing and regeneration of injured cartilage. Chondrocytes and/or mesenchymal stem cells may be used along with this invention.
Inventor: Mansmann, Kevin A. (Paoli, PA
Assignee: None Stated
Date of First Priority Issue: Thursday September 10th, 1998
Patent Number: 6551355
This patent covers various biocompatible coating compositions that in one embodiment are used to decrease immunogenecity of bone grafts.
Inventors: Lewandrowski, Kai-Uwe (Brookline, MA); Bondre, Shrikar (Malden, MA); Trantolo, Debra J. (Princeton, MA); Cattaneo, Maurice V. (Quincy, MA); Gresser, Joseph D. (Brookline, MA); Wise, Donald L. (Belmont, MA)
Assignee: Cambridge Scientific, Inc. (Cambridge, MA)
Date of First Priority Issue: Friday August 14th, 1998
Patent Number: 6080581
This patent covers a method of generating three dimensional tissues in culture. The culture system allows for continuous addition of media and growth factors as well as escape of waste products.
Inventors: Anderson, Charles Daniel (Houston, TX); Dodd, Charlie W. (Seabrook, TX)
Assignee: None stated
Date of First Priority Issue: Thursday July 2nd, 1998
Patent Number: 6171610
This patent covers hydrogels that may be used in combination with stem cells for the generation of various artificial tissues.
Inventors: Vacanti, Charles A. (Uxbridge, MA); Vacanti, Joseph P. (Winchester, MA); Vacanti, Martin P. (Westborough, MA)
Assignee: University of Massachusetts (Boston, MA) The Children's Medical Center Corporation (Boston, MA)
Date of First Priority Issue: Friday April 24th, 1998
Patent Number: 6027744
This patent covers ways generating tissue implants and artificial tissues in vitro for in vivo implantation.
Inventors: Vacanti, Charles A. (Worcester, MA); Vacanti, Joseph P. (Worcester, MA)
Assignee: University of Massachusetts Medical Center (Boston, MA) The Children's Medical Center Corporation (Boston, MA)
Date of First Priority Issue: Friday April 24th, 1998
Patent Number: 6103528
This patent teaches how to make a tissue culture media which gells upon treatment or exposure to specific conditions. The advantage of this is that cells can be added when the media is liquid, and then the gelling characteristic can be used for the formation of specially shaped structures, structures which can subsequently be implanted.
Inventors: An, Yuehuei H. (Charleston, SC); Mironov, Vladimir A. (Mt. Pleasant, SC); Gutowska, Anna (Richland, WA)
Assignee: Battelle Memorial Institute (Richland, WA) Medical University of South Carolina (Charleston, SC)
Date of First Priority Issue: Friday April 17th, 1998
Patent Number: 6637437
This patent provides novel cellular "fillers" that are generated in culture specifically for the patient, and administered during head and neck surgery in order to "fill the gap".
Inventors: Hungerford, David S. (Cockeysville, MD); Frondoza, Carmelita G. (Woodstock, MD); Shikani, Alan H. (Ruxton, MD); Domb, Abraham J. (Efrat, IL)
Assignee: Johns Hopkins University (Baltimore, MD) Chondros, Inc. (Baltimore, MD)
Date of First Priority Issue: Wednesday April 8th, 1998
Patent Number: 6143293
This patent covers a multilayered scaffold that can be seeded with stem cells, other types of cells, and/or growth factors for the generation of three dimensional tissues in culture.
Inventors: Weiss, Lee E. (Pittsburgh, PA); Calvert, Jay Wynn (Pittsburgh, PA)
Assignee: Carnegie Mellon (Pittsburgh, PA) University of Pittsburgh (Pittsburgh, PA)
Date of First Priority Issue: Thursday March 26th, 1998
Patent Number: 7,270,829
This patent teaches what a friend of mine used to call the notion of "biobeef". The concept of generating edible meat through tissue culture. The patent has one independent claim which essentially covers the use of cultured cells to generate a three dimensional tissue that can be eaten that does not require "deboning, removal of offal and/or tendon and/or gristle and/or fat".
This patent...
Inventors: Van Eelen; Willem Frederik (Amsterdam, NL)
Assignee: None Stated
Date of First Priority Issue: Thursday December 18th, 1997
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