Patents (1374 Stem Cell Patents)

Class: 3D Culture/Scaffold (89)

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Resurfacing cartilage defects with chondrocytes proliferated without differentiation using platelet-derived growth factor

Patent Number: 6001352

This patent teaches the use of platelet derived growth factor for stimulating proliferation of chondrocyte and chondrocyte stem cells along the area of a joint defect, so as to accelerate healing.

Inventors: Boyan, Barbara D. (San Antonio, TX); Schwartz, Zvi (Jerusalem, IL)
Assignee: OsteoBiologics, Inc. (San Antonio, TX)
Date of First Priority Issue: Monday March 31st, 1997

Bioartificial filtration device for filtering blood to mimic kidney function

Patent Number: 6942879

This patent is for a bioartificial kidney suitable for a variety of uses, including in patients with renal failure. The patent has one independent claim covering a filtration device which contains a layer of non-immortalized renal endothelial cells, non-immortalized renal epithelial cells, or a mixture thereof, and (ii) pericytes, vascular smooth muscle cells. This approach is currently in...

Inventor: Humes, H. David (Ann Arbor, MI)
Assignee: The Regents of the University of Michigan (Ann Arbor, MI)
Date of First Priority Issue: Monday September 30th, 1996

Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo

Patent Number: 6150164

This patent teaches how to make a cell-seeded bioreactor so as to grow various types of kidney cells onto a hollow fiber filter for the generation of an "artificial kidney".

Inventor: Humes, H. David (Ann Arbor, MI)
Assignee: The Regents of the University of Michigan (Ann Arbor, MI)
Date of First Priority Issue: Monday September 30th, 1996

Biocompatible devices with foam scaffolds

Patent Number: 6054142

This patent provides scaffolds that can be seeded with stem cells and subsequently inplanted for regeneration of various tissues.

Inventors: Li, Rebecca (Canton, MA); Hazlett, Tyrone F. (Coventry, RI)
Assignee: Cyto Therapeutics, Inc. (Lincoln, RI)
Date of First Priority Issue: Thursday August 1st, 1996

Cell seeding of ceramic compositions

Patent Number: 6544290

This patent provides cell scaffolds made of a variety of materials, including ceramic. These scaffolds are useful for the growth of various tissues both in vitro and in vivo.

Inventors: Lee, Dosuk D. (Brookline, MA); Rey, Christian (Castanet, FR); Aiolova, Maria (Brookline, MA)
Assignee: Etex Corporation (Cambridge, MA)
Date of First Priority Issue: Friday May 19th, 1995

Preparation of cell seeded ceramic compositions

Patent Number: 6139578

This patent provides scaffolds and various compositions for their manufacture so that the structures made may be seeded with stem cells and/or other types of cells for tissue engineering purposes.

Inventors: Lee, Dosuk D. (Brookline, MA); Rey, Christian (Castanet, FR); Aiolova, Maria (Brookline, MA)
Assignee: Etex Corporation (Cambridge, MA)
Date of First Priority Issue: Friday May 19th, 1995

Cell seeding of ceramic compositions

Patent Number: 6132463

This patent covers compositions of matter useful for generation of bone grafts and artificial bones either in vitro or in vivo.

Inventors: Lee, Dosuk D. (Brookline, MA); Rey, Christian (Castanet, FR); Aiolova, Maria (Brookline, MA)
Assignee: Etex Corporation (Cambridge, MA)
Date of First Priority Issue: Friday May 19th, 1995

Resorbable extracellular matrix for reconstruction of cartilage

Patent Number: 7,208,177

The current patent covers a matrix that is useful for treatment of cartilage injuries. The matrix disclosed is resorbable at a controlled rate and contains collagen II either from autologous, allogeneic, or xenogeneic sources. Specific pore sizes and additives are claimed. The patent is useful for parties seeking methods of introducing cells or growth factors to accelerate cartilage...

Inventors: Geistlich; Peter (Stansstad, CH), Schloesser; Lothar (Darmstadt, DE)
Assignee: Ed. Geistlich Soehne AG fuer Chemische Industrie (Wolhusen, CH)
Date of First Priority Issue: Wednesday February 22nd, 1995

Bioartificial extracellular matrix containing hydrogel matrix derivatized with cell adhesive peptide fragment

Patent Number: 6156572

This patent provides novel compositions of matter that are useful for growing stem cells and neurons derived thereof for the purpose of implantation into the host. Specific matrices are provided.

Inventors: Bellamkonda, Ravi (Boston, MA); Ranieri, John P. (Lausanne, CH); Aebischer, Patrick (Lutry, CH)
Assignee: Neurotech S.A. (Evry, FR)
Date of First Priority Issue: Wednesday July 20th, 1994

Control of cell growth in a bioartificial organ with extracellular matrix coated microcarriers

Patent Number: 5858747

This patent covers several means of growing stem cells and their derivatives, as well as generating scaffolds and implantable means that protect the stem cells from the immunological reaction of the host.

Inventors: Schinstine, Malcolm (Ben Salem, PA); Shoichet, Molly S. (Toronto, CA); Gentile, Frank T. (Warwick, RI); Hammang, Joseph P. (Barrington, RI); Holland, Laura M. (Horsham, PA); Cain, Brian M. (Everett, MA); Doherty, Edward J. (Mansfield, MA); Winn, Shelley R
Assignee: CytoTherapeutics, Inc.
Date of First Priority Issue: Wednesday July 20th, 1994

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