Class: 3D Culture/Scaffold (89)
Method for controlling proliferation and differentiation of cells encapsulated within bioartificial organs
Patent Number: 5795790This patent teaches the use of UV irradiation in order to render encapsulated cells mitotically inactive, but still metabolically active. This patent is useful for the generation of grafts that are implantable, for example an artificial pancreas.
Biomatrix for soft tissue regeneration using mesenchymal stem cells
Patent Number: 6174333This patent covers implantable agents that can be administered together with mesenchymal stem cells for the purpose of creating or repairing various tissues.
Manufacture of autogenous replacement body parts
Patent Number: 6110482This patent teaches how to make artificial joints using stem cells and various devices and systems.
Method and construct for producing graft tissue from an extracellular matrix
Patent Number: 6398819This patent teaches ways of decellularizing tissue, including xenogeneic tissue, so that it may be used as a scaffold to be seeded with human stem cells, and then the stem cells plus tissue scaffold are implanted into the human as an artificial composite tissue.
Method and construct for producing graft tissue from an extracellular matrix
Patent Number: 5800537This patent teaches how to decellularize various tissues and to use the remnants as a scaffold for seeding of stem cells. This patent is useful for tissue engineering of varous organs and anatomical structures.
Methods and compositions for isolation and growth of kidney tubule stem cells, in vitro kidney tubulogenesis and ex vivo construction of renal tubules
Patent Number: 6060270This patent teaches how to grow kidney tubules from renal stem cells, and how to use these for making a hollow fiber filter that resembles an artificial kidney.
Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo
Patent Number: 5549674This patent covers an artificial kidney system designed in a manner so as to combine hollow fiber technology with living, fresh endothelial cells. This patent does mention that in some embodiments stem cells may be used for providing the necessary cells. Various artificial kidneys have been designed and the author of this patent has actually been involved in their clinical development...
Methods for treating disease and forming a supplemented fibrin matrix
Patent Number: 7,208,179The current patent covers various compositions of matter for manufacturing tissue sealants. The sealants covered contain various growth factors, either recombinantly produced and added, or added through activation of cells. The sealants described are potentially synergistic with stem cells for acceleration of wound healing.
Process and media for the growth of human cornea and gingiva
Patent Number: 5912175This patent teaches how to grow specialized epithelial structures from stem cells such as cornea, gingiva, and ureters. Specific tissue culture conditions and media are provided for growing the stem cells and inducing their differentiation into the desired tissue.
Matrix for tissue engineering formed of a hyaluronic acid ester and hydrolyzed collagen
Patent Number: 6737072This patent covers a matrix that is made of hyaluronic acid and hydrolyzed collagen, that can be used as a scaffold for in vitro three dimensional tissue generation, or can be seeded with stem cells and implanted in vivo.