Class: 3D Culture/Scaffold (88)
Method for producing non-neoplastic, three dimensional, mammalian tissue and cell aggregates under microgravity culture conditions and the products produced therefrom
Patent Number: 5496722This patent teaches the generation of three dimensional tissues through culture under microgravity conditions. This patent discloses several culture conditions, as well as scaffolds, that can be utilized for the generation of the three dimensional organ or organoid structure.
Three-dimensional culture of pancreatic parenchymal cells cultured living stromal tissue prepared in vitro
Patent Number: 6022743This patent teaches the three dimensional generation of artificial pancreatic grafts using a proprietary culture system that is described in detail.
Three-dimensional stromal tissue cultures
Patent Number: 5962325This patent teaches how to generate three dimensional cultures of stem cells through the use of special metrices and TGF beta. The three dimensional cultures can be generated using a variety of stem cells including mesenchymal stem cells. The mesenchymal stem cells may be extracted from bone marrow, cord blood or other sources.
Three-dimensional bone marrow cell and tissue culture system
Patent Number: 5541107In this patent regarding bone marrow stem cell culture, Advanced Tissue Sciences continues their tour de force in three dimensional culture IP, through covering the use of three dimensional cultures for expanding bone marrow stem cells. Specifically, the patent teaches that stromal cells and a three dimensional matrix can be used for expansion of hematopoietic...
Three-dimensional pancreatic cell and tissue culture system
Patent Number: 5516681This patent teaches the use of stromal cells to support growth, proliferation, and differentiation of islet-like pancreatic structures after addition of pancreatic acinar cells to the culture. This technology can be a great basis for the numerous other stem cell technologies currrently available for islet regeneration.
Three-dimensional kidney cell and tissue culture system
Patent Number: 5516680This patent teaches the generation of artificial kidneys through culturing of various cells that comprise the functional kidney in a three dimensional stromal preparation. The patent may be used not only for addition of kidney stem cells, but can incorporate various types of adult and embryonic stem cells for generation of "younger" kidneys.
Three-dimensional skin cell and tissue culture system
Patent Number: 5512475This patent teaches how to generate artificial skin through culturing of stem cells in a three dimensional matrix. Artificial skin is very useful not only for burn patients, but also for in vitro testing of topical drug formulations. The invention uses a stromal cell preparation onto which melanocytes and keratinocytes are added.
Three-dimensional cell and tissue culture system
Patent Number: 5443950This patent claims a three dimensional structure that can be grown in vitro using stromal cells, stem cells, and other cell types, for the generation of tissue. The structure can then be introduced in vivo either to function as an organ, or to assist the function of an existing body component.