Class: Type (175)
Mesenchymal precursor cell
Patent Number: 7,399,632Mesenchymal stem cell therapy is rapidly becoming a clinical reality. The beauty of this cell population is that it can be used in an "off the shelf" manner and does not appear to have many safety issues. Mesenchymal stem cells from the bone marrow have been patented by Osiris, whereas cells similar to mesenchymal stem cells have been...
1 Comment
Pluripotent adult stem cells
Patent Number: 7,259,011This patent covers a stem cell that is positive for expression of CD13, CD34, CD56 and CD117, negative for CD10. Dependent claims further cover the phenotype of CD2, CD5, CD14, CD19, CD33, CD45, and DRII negative, CD13,CD34, CD56, CD90, CD117... It has previously been demonstrated that rat hepatic cells can be coaxed into producing insulin by isolating the hepatic cells from an animal that was first primed with a hepatoxin, and subsequently exposing the isolated hepatic cells to high glucose concentrations.
In the current patent a hepatic cell line that has been... This patent covers a new method of cloning cows. Specifically, the patent teaches a method of making a cow blastocyst by - extracting a primordial gamete cell population from the cow fetus This patent covers methods of isolating neural stem cells using antibodies that bind CD49f. The first independent claim is very broad in that it is not restricted to originating material of adult or embryonic origin but simply covers a method of purifying a population by selecting for cells that initiate neurospheres in culture and express CD49f. CD49f is found on other types of stem cells as... This patent is highly interesting in that the inventors claim to have devised a simple and easy to implement methodology for generation of autologous stem cells. Essentially, the invention teaches that culturing of peripheral blood monocytes in the presence of IL-3 and M-CSF for approximately 6 days, somehow induces a program of de-differentiation in the monocytes to endow them with stem... Stem cell populations are known from the cord blood as well as the placental matrix. In the current patent a stem cell population from the placenta is covered that possesses markers of adult stem cells as well as embryonic stem cells.
For example, the first claim covers... This patent covers the use of epigenetically reprogramming a donor nucleus prior to cloning. Essentially Collas uses methods he previously described as able to induce dedifferentiation of adult cells. In previous papers, Collas demonstrated that tranfering cytoplasm from a T cell into a fibroblast (through temporarily permeabilizing the fibroblast), will allow the fibroblast to express T cell... This patent has one claim that covers a specific mesenchymal stem cell population that is immortalized and appears to contain a gene associated with immortalization. This patent teaches methods of generating a composite blastocyst from non-viable embryos. The invention is useful for generation of stem cells of embryonic origin through a novel method.
Insulin-secreting immortalized liver cell line modified by glucose sensitivity
Patent Number: 7,312,077
Efficient nuclear transfer with primordial gametes
Patent Number: 7,351,876
- using the nucleus of the primordial gamete cell as a nuclear donor for an enucleated oocyte
- and activating the combination of the primordial gamete nucleus with the recipient... 1 Comment
Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations
Patent Number: 7,381,561
Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
Patent Number: 7,138,275
8 Comments
Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
Patent Number: 7,311,905
2 Comments
Methods for cloning non-human mammals using reprogrammed donor chromatin or donor cells
Patent Number: 7,253,334
Immortalized bone marrow mesenchymal stem cell
Patent Number: 6645763
Composite blastocysts (CBs) from aggregates of dissociated cells of non-viable pre-embryos
Patent Number: 6759244