Three dimensional bioengineered smooth muscle tissue and sphincters and methods therefor
Patent Number: 7,368,279
Date of First Priority Issue: Wednesday November 24th, 2004
Date Issued: Tuesday May 6th, 2008
Assignee: The Regents of The University of Michigan (Ann Arbor, MI)
Inventors: Bitar; Khalil N. (Ann Arbor, MI), Hecker; Louise (Ann Arbor, MI), Baar; Keith (Dundee, GB), Somara; Sita (Ypsilanti, MI)
From Class: 3D Culture/Scaffold
Comments: No comments
This patent covers methods of producing artificial sphincters. Specifically, smooth muscle cells are grown on an extracellular matrix that is placed on a tissue culture vessal coated with polydimethyl siloxane and a mold made of a cylindrical shape which is coated with the same material. Examples of extracellular matrices useful for the invention include fibrin. The patent covers a variety of sphincters including internal anal and sphincters of the gastrointestinal tract.
Sphincter repair is currently in clinical trials from several companies, including the French biotechnology company Celogos.
View this patent on the USPTO website.
Added to StemCellPatents.com on Sunday May 11th, 2008
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