Isolation of neural stem cells using gangliosides and other surface markers
Patent Number: 7,419,825
Date of First Priority Issue: Friday April 20th, 2001
Date Issued: Tuesday September 2nd, 2008
Assignee: Children's Hospital of Orange County (Orange, CA)
Inventors: Klassen; Henry (Pasadena, CA), Schwartz; Michael (Garden Grove, CA), Young; Michael J. (Gloucester, MA)
From Class: Extraction/Preservation
Comments: No comments
This patent covers a method of isolating neural stem cells by the surface marker CD15. This protein is found on neutrophils and other immune cells, known more for its adhesion functions and sugar-binding activity. Previously another patent (US # 7,182,946) touched upon the utility of this marker for purification of neural stem cells.
The patent does not discriminate sources for purification of neural stem cells and includes brain, retina, spinal cord, fetal tissue, and adult tissues.
Other markers of neural stem cells include CD133.
View this patent on the USPTO website.
Added to StemCellPatents.com on Saturday September 6th, 2008
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