Why Sorted CXCR4+ and CXCR4- Stem Cells Have Similar Engraftment
Sunday July 8th, 2007 @ 14:43:34 EST
From Category: Migration
Comments: 1 (Show Comments)
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This video reviews data that explains why CXCR4+ stem cells and CXCR4- stem cells home with similar efficiency to the bone marrow. The answer is that the CXCR4 antibody actually blocks signalling, and that CXCR4- cells actually contain intracellular stores of CXCR4 which can be upregulated by cytokines.
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Orit Kollet said...
To the presenter:
It is a very clear and coherent presentation, and I greatly enjoyed listening to your talk interpreting our work. I am curious to know for which audience and what circumstances this presentation was prepared for.
Thank you for a well done job!
Orit Kollet