Autologous Adipose for Multiple Sclerosis

The use of autologous stem cell therapy has many theoretical and practical advantages.  Autologous bone marrow mononuclear cells were originally used for treatment of ischemic heart failure, and subsequently to prevent post-infarct remodeling.  Numerous other uses of autologous fat derived stem cells have also been reported.  Adipose mononuclear cells have demonstrated positive effects in pigs with heart failure, as well as ability to revert neurological damage in a model of cerebral palsy.

For example, the company Cytori is currently performing clinical trials using lipoaspirate mononuclear cells as a substitute for bone marrow in the treatment of post-infarct heart failure. 

A recent news report covered a report of a Texas policeman with multiple sclerosis that was successfully treated with autologous fat derived cells.  To our knowledge this is the first report of a case of autoimmunity treated with this approach. 

Theoretically, autologous adipose cells represent an ideal approach to conditions such as multiple sclerosis because on the one hand they provided immune modulation, on the other hand they provide a cellular sources for remyelination. 

1 Comment | Add Comment