G-CSF of Blood and Brain

Tuesday November 28th, 2006 @ 20:04:14 EST

From Category: Neural

Loma Linda CA-

We at StemCellPatents.com have described in various patents the relationship between hematopoietic stem cells and neural stem cells. Stunning examples include the ability of neurons to stimulate hematopoiesis, Patent # 6897060, the ability of the same hypoxic conditions that promote hematopoietic stem cell expansion to expand neural stem cells, Patent # 6924142, and the ability of neurons to transdifferentiate into hematopoietic stem cells, Patent # 6093531 .

In a review paper that appeared online today, Solaroglu et al discuss evidence that the clinically used cytokine G-CSF may be neuroprotective. The paper, entitled "Neuroprotective effect of granulocyte-colony stimulating factor" which appeared in Front Biosci. 2007 Jan 1;12:712-24 provides numerous animal model and theoretical examples as to why G-CSF administration may be useful in stroke.

The fact that G-CSF is already clinically tested for treatment of neurodegeneration in China supports the notion that there may be some rationale for this hypothesis.

Social & Bookmarking:Digg 'G-CSF of Blood and Brain' Add 'G-CSF of Blood and Brain' to del.icio.us Add 'G-CSF of Blood and Brain' to Technorati Stumble 'G-CSF of Blood and Brain' Add 'G-CSF of Blood and Brain' to Furl Add 'G-CSF of Blood and Brain' to Reddit Add 'G-CSF of Blood and Brain' to Blinklist Add 'G-CSF of Blood and Brain' to Ma.gnolia Share 'G-CSF of Blood and Brain' on Facebook Add 'G-CSF of Blood and Brain' to Google Add 'G-CSF of Blood and Brain' to Yahoo Web 

1 Comment | Add Comment

Michael said...

Created 2006-11-28 20:16:08 EST

Do patients taking G-CSF for hematological malignancies have increases in mental function??

- 1 -

Add Comment

You must be signed-in to add your comments.

now or Join the StemCellPatents.com Community for free.

Home | News | Patents | Products | Jobs | Links | Search | Journal | RSS

About | Advisory Board | Newsletter | Advertise | Contact | Sitemap | Privacy Policy | Terms of Use

Copyright © 2006 - 2024 StemCellPatents.com - All rights reserved. - Toronto Web Design

StemCellPatents.com V2.04

Stouffville Concrete | Tottenham Concrete | Uxbridge Concrete | Gerogetown Concrete | Rockwood Concrete | Kleinburg Concrete | Stouffville Real Estate Agent