StemCellPatents.com Newsletter

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Last week an interesting patent was issued, #7,482,332, covering a type of nano-circle DNA construct that may be administered to cells to prevent telomere shortening and presumably senescence.  The inventors are proposing this to be an alternative to having to physicially transfect with the hTERT gene. 

Other patents issued last week include #7,482,025, which covers methods of using decellularized liver for assisting tissue regrowth, as well as # 7,483,749 covering use of electrical pulses to stimulate cardiac regeneration.

In the news, our friends who are dentists will enjoy hearing that periodontal ligament derived mesenchymal stem cells, as well as gingival fibroblasts, have immune modulatory activities similar to bone marrow mesenchymal stem cells, mediated through TGF-beta, HGF, and induction of IDO activity.

Additionally, for those of you who missed the announcement we made earlier in the week, the company International Stem Cell (ISCO) is making progress in using parthenogenic derived stem cells for growing of corneal tissue. 

As a last note, we would like to wish a very happy birthday to Eli Sercarz, one of the most inspiring immunologists and human beings.

Telomere-encoding synthetic DNA nanocircles, and their use for the elongation of telomere repeats     Patent Number: 7,482,332 Assignee | Inventor Telomeres are repeats of the TTAGGG sequence on the ends of chromosomes that progressively get shorter with each cell division, causing eventual cell senescence.  The enzyme telomerase is important in cells that need to proliferate longer, for example memory T cells, or stem cells.  It is a dream of many to...[Read More] Ask a question OR leave your comments.

Periodontal Ligament Mesenchymals are Immune Suppressive Sunday February 1st, 2009 @ 17:42:33 EST Mesenchymal stem cells, or cells resembling these cells, have been found in a variety of different tissues in addition to the bone marrow.  These include, fat, menstrual blood and teeth.  One interesting question is how these cells differ from each...[Read More] 1 Comment Ask a question OR leave your comments. Read more StemCellPatents.com News

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RECENTLY ADDED PATENTS     Mammary stem cell marker (7,563,619) Assignee | Inventor | Ask a question OR leave your comments     Soft tissue repair and regeneration using postpartum-derived cells (7,560,276) Assignee | Inventor | Ask a question OR leave your comments     Compositions and methods for generating skin (7,560,275) Assignee | Inventor | Ask a question OR leave your comments     Method for reducing neuronal degeneration so as to ameliorate the effects of injury or disease (7,560,102) Assignee | Inventor | Ask a question OR leave your comments     Human cord blood derived unrestricted somatic stem cells (USSC) (7,560,280) Assignee | Inventor | Ask a question OR leave your comments     Human cord blood derived unrestricted somatic stem cells (USSC) (7,556,801) Assignee | Inventor | Ask a question OR leave your comments     Dedifferentiated, programmable stem cells of monocytic origin, and their production and use (7,553,663) Assignee | Inventor | Ask a question OR leave your comments     Stromal antigen-presenting cells and use thereof (7,553,661) Assignee | Inventor | Ask a question OR leave your comments     Directed in vitro differentiation of marrow stromal cells into neural cell progenitors (7,547,545) Assignee | Inventor | Ask a question OR leave your comments     Progenitor cells from wharton's jelly of human umbilical cord (7,547,546) Assignee | Inventor | Ask a question OR leave your comments     View all 1436 Stem Cell Patents on StemCellPatents.com

LATEST NEWS     Leptin Blocks T Regulatory Cell Expansion August 23rd, 2009     Mechanism of Multiple Sclerosis Stem Cell Therapy July 24th, 2009 : 2 Comments     Lithium for Treatment of Multiple Sclerosis July 15th, 2009     Treatment of Degenerative Disc Disease by Bone Marrow Stem Cells July 9th, 2009 : 2 Comments     Apoptotic Cells Secrete Angiogenic Factors June 27th, 2009     Read more news on StemCellPatents.com

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