Class: Use (276)
Method for the treatment of grafts prior to transplantation using TGF-.beta .
Patent Number: 5135915This is a patent covering the de-immunization of an organ by treatment with TGF-b before transplantation. The organs that may be used include heart, liver, spleen, pancreas, thyroid lobe, lung, kidney, intestine, blood vessel, and esophagus. The use of TGF bet to decrease immunogenecity is supported by other observations that this...
Method of regenerating or replacing cartilage tissue using amniotic cells
Patent Number: 5612028This patent teaches the use of stem cells derived from amniotic tissue for regeneration of cartilage tissue. The stem cells of the amniotic tissue claimed are epithelial and free of mesenchymal tissue.
Gene transfer using transformed, neodetermined, embryonic cells
Patent Number: 5032407This patent teaches that embryonic yolk sac, midbrain, and forbrain cells may be gene transfected with a useful gene and utilized as a vector for delivery of the gene to an area of need.
Method for recombinant production of human pluripotent granulocyte colony-stimulating factor
Patent Number: 5830705This is a patent on ways of generating a cytokine called human p-G-CSF. I wonder what the modern name of this cytokine is? In any case, the invention teaches that this cytokine stimulates hematopoietic stem cells proliferation.
Methods of enhancing bone marrow transplantation and treating burn wounds comprising administering human pluripotent granulocyte colony-stimulating factor
Patent Number: 5676941Like other hematopoietic cytokines, this patent teaches that hpG-CSF may be administered for the treatment of burn wounds.
Methods of treating bacterial inflammation and granulocytopoiesis by administering human pluripotent granulocyte colony-stimulating factor
Patent Number: 5582823This patent covers the use of human pluripotent granulocyte colony stimulating factor for induction of granulocyte production, as well as for reducing bacterially mediated inflammation. The use of growth factors such as the one described has expanded in recent years to other types of stem cells besides hematopoietic stem cells. It will be interesting to see first what the new name for the...