Class: Type (195)
Mesenchymal precursor cell
Patent Number: 7,399,632Mesenchymal stem cell therapy is rapidly becoming a clinical reality. The beauty of this cell population is that it can be used in an "off the shelf" manner and does not appear to have many safety issues. Mesenchymal stem cells from the bone marrow have been patented by Osiris, whereas cells similar to mesenchymal stem cells have been...
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Mammary stem cell marker
Patent Number: 7,563,619Cancer stem cells are considered the "Seed" or the "root" of the cancer, and like chopping down a tree, if you dont remove the root, the cancer grows back. Cancer stem cells are resistant to chemotherapy and radiotherapy. Therefore if there was a way to selectively purify or extract cancer stem cells, it would make it a lot...
Pluripotent adult stem cells
Patent Number: 7,259,011This patent covers a stem cell that is positive for expression of CD13, CD34, CD56 and CD117, negative for CD10. Dependent claims further cover the phenotype of CD2, CD5, CD14, CD19, CD33, CD45, and DRII negative, CD13,CD34, CD56, CD90, CD117... Continuing Novocell's domination of IP in the area of developing commercial ES-derived products, this recent patent covers composition of matter on in vitro endoderm (eg progenitor cell of the liver, pancreas, digestive tube) derived from "multipotent" cells. The broadest claim, "An in vitro cell culture comprising human cells wherein at least 15% of said... The hematopoietic stem cell is the most well studied stem cell, being responsible for saving hundreds of thousands of lives through allowing the procedure of bone marrow transplant to become a reality. As far back as 1984, filings on hematopoietic stem cells can be found (#4,714,680). The current patent has a new way of purifying hematopoietic stem... This patent covers methods of isolating the megakaryocytic progenitor cells through selecting for cells that are positive for CD41, CD, and CD34 and negative for expression of CD2; CD3; CD4; CD7; CD8; CD10; CD11b; CD14; CD19; CD20; CD56; and glycophorin A. Starting materials for selection of these cells include bone marrow and mobilized peripheral blood. Platelet deficiency is... The liver is one of the organs that has been demonstrated to respond to stem cell therapy both in animal models and in clinical trials. It is known that the liver has endogenous stem cells, but also that bone marrow stem cells can differentiate into liver cells. In fact, it is published that... It has previously been demonstrated that rat hepatic cells can be coaxed into producing insulin by isolating the hepatic cells from an animal that was first primed with a hepatoxin, and subsequently exposing the isolated hepatic cells to high glucose concentrations.
In the current patent a hepatic cell line that has been... This patent covers a new method of cloning cows. Specifically, the patent teaches a method of making a cow blastocyst by - extracting a primordial gamete cell population from the cow fetus This patent covers methods of isolating neural stem cells using antibodies that bind CD49f. The first independent claim is very broad in that it is not restricted to originating material of adult or embryonic origin but simply covers a method of purifying a population by selecting for cells that initiate neurospheres in culture and express CD49f. CD49f is found on other types of stem cells as...
Definitive endoderm
Patent Number: 7,510,876
Hematopoietic stem cell identification and isolation
Patent Number: 7,510,877
Mammalian megakaryocyte progenitor cell
Patent Number: 7,494,807
Primitive and proximal hepatic stem cells
Patent Number: 7,413,897
Insulin-secreting immortalized liver cell line modified by glucose sensitivity
Patent Number: 7,312,077
Efficient nuclear transfer with primordial gametes
Patent Number: 7,351,876
- using the nucleus of the primordial gamete cell as a nuclear donor for an enucleated oocyte
- and activating the combination of the primordial gamete nucleus with the recipient... 1 Comment
Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations
Patent Number: 7,381,561