Retro-inverso peptides derived from interleukin-3
Patent Number: 7,115,571
Date of First Priority Issue: Friday June 16th, 2000
Date Issued: Tuesday October 3rd, 2006
Assignee: Myelos Corporation (Iselin, NJ)
Inventors: Wright; David E. (Ramona, CA), Parks; D. Elliott (Del Mar, CA)
From Class: Expansion
Comments: No comments
IL-3 is a potent expander of hematopoietic stem cells. Unfortunately administration of proteins is associated with poor pharmacokinetics and the need to develop special formulations that can systemically deliver the protein.
This patent covers peptide derivatives of IL-3 which have improved activity and pharmacological activity compared to administration of the whole protein.
This patent is useful not only for hematopoietic stem cell expansion but could be applied to neuronal, cardiac, or pro-angiogenic stem cells.
View this patent on the USPTO website.
Added to StemCellPatents.com on Saturday November 11th, 2006
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