Method for neural stem cell differentiation using valproate
Patent Number: 7,132,286
Date of First Priority Issue: Monday June 18th, 2001
Date Issued: Tuesday November 7th, 2006
Assignee: Psychiatric Genomics, Inc. (Gaithersburg, MD)
Inventors: Laeng; Pascal (Washington, DC), Mallon; Barbara (Gaithersburg, MD), Pitts; Lee (Falls Church, VA)
From Class: Differentiation
Comments: No comments
This patent covers the use of valproic acid for inducing differentiation of neurons from neural stem cells.
This patent seems to be restricted in the claims to the in vitro differentiation of neurons. What is interesting is whether the concentrations claimed in the patent are actually achievable in vivo.
Since valproic acid is clinically used as an anticonvulsant, it is interesting to speculate whether its activities are related to augmentation of stem cells in vivo.
View this patent on the USPTO website.
Added to StemCellPatents.com on Saturday November 11th, 2006
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